Blar i forfatter Det helsevitenskapelige fakultet "Rad, Amir"

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    • 13-Type HPV DNA Test versus 5-Type HPV mRNA Test in Triage of Women Aged 25–33 Years with Minor Cytological Abnormalities–6 Years of Follow-Up 

      Rad, Amir; Sørbye, Sveinung; Brenn, Tormod; Tiwari, Sweta; Løchen, Maja-Lisa; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)
      Background: A specific, cost-effective triage test for minor cytological abnormalities is essential for cervical cancer screening among younger women to reduce overmanagement and unnecessary healthcare utilization. We compared the triage performance of one 13-type human papillomavirus (HPV) DNA test and one 5-type HPV mRNA test. Methods: We included 4115 women aged 25–33 years with a screening ...

    • HPV mRNA and HPV DNA Tests in Cervical Cancer Screening 

      Rad, Amir (Doctoral thesis; Doktorgradsavhandling, 2023-11-09)
      <p><i>Background:</i> Cervical cancer is the fourth most prevalent cancer in women worldwide. Cervical cancer screening (cytology or human papillomavirus [HPV] testing) and HPV vaccination can decrease cervical cancer incidence and mortality. However, because cytology-based screening has a low sensitivity to detect high-grade cervical lesions, several countries have replaced it with HPV test-based ...

    • HPV types in cervical cancer tissue in South Africa: A head-to-head comparison by mRNA and DNA tests 

      Rad, Amir; Sørbye, Sveinung Wergeland; Dreyer, Greta; Hovland, Siri; Falang, Bente Marie; Louw, Melanie; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-01)
      <p>Accurate identification of human papillomavirus (HPV)-types in cervical cancer tissue may be important for tailoring tests for primary screening and types to be included in a vaccine. The aim of this study was to compare test-performance of a 45-type HPV deoxyribonucleic acid (DNA)-test with a 9-type HPV messenger ribonucleic acid (mRNA)-test in cervical cancer tissues. <p>In a case-series design ...

    • Risk of Intraepithelial Neoplasia Grade 3 or Worse (CIN3+) among Women Examined by a 5-Type HPV mRNA Test during 2003 and 2004, Followed through 2015 

      Rad, Amir; Sørbye, Sveinung; Tiwari, Sweta; Løchen, Maja-Lisa; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-08)
      <p><i>Background:</i> The study’s purpose was to evaluate the performance of a five-type HPV mRNA test to predict cervical intraepithelial neoplasia grade 3 or worse (CIN3+) during up to 12 years of follow-up. <p><i>Methods:</i> Overall, 19,153 women were recruited by gynecologists and general practitioners in different parts of Norway between 2003 and 2004. The study population comprised 9582 ...