Canzian, Federico; Lund, Eiliv; Kaaks, Rudolf; Cox, David G.; Henderson, Katherine D.; Henderson, Brian E.; Berg, Christine; Bingham, Sheila; Boeing, Heiner; Buring, Julie; Calle, Eugenia E.; Chanock, Stephen; Clavel-Chapelon, Francoise; Dossus, Laure; Feigelson, Heather Spencer; Haiman, Christopher A.; Hankinson, Susan E.; Hoover, Robert; Hunter, David J.; Isaacs, Claudine; Lenner, Per; Overvad, Kim; Palli, Domenico; Pearce, Celeste Leigh; Quiros, Jose R.; Riboli, Elio; Stram, Daniel O.; Thomas, Gilles; Thun, Michael J.; Trichopoulos, Dimitrios; van Gils, Carla H.; Ziegler, Regina G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-29)
Background: Gonadotropin releasing hormone (GNRH1) triggers the release of follicle
stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene
encoding GNRH1 or its receptor may influence breast cancer risk by modulating production of
ovarian steroid hormones. We studied the association between breast cancer risk and
polymorphisms in genes that code for GNRH1 ...