• Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study 

      Llaha, Fjorida; Cayssials, Valerie; Farràs, Marta; Agudo, Antonio; Sandström, Maria; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Laouali, Nasser; Truong, Thérèse; Le Cornet, Charlotte; Katzke, Verena; Schulze, Matthias; Palli, Domenico; Krogh, Vittorio; Signoriello, Simona; Tumino, Rosario; Ricceri, Fulvio; Skeie, Guri; Jensen, Torill Miriam Enget; Chen, Sairah Lai Fa; Lasheras, Cristina; Rodriguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Guevara, Marcela; Almquist, Martin; Nilson, Lena Maria; Hennings, Joakim; Papier, Keren; Heath, Alicia; Weiderpass, Elisabete; Rinaldi, Sabina; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-02)
      Background: The Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods: ...
    • Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Nadal-Zaragoza, Núria; Tjønneland, Anne; Mellemkjær, Lene; Hajji-Louati, Mariem; Truong, Thérèse; Katzke, Verena; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Di Girolamo, Chiara; Skeie, Guri; Borch, Kristin Benjaminsen; Olsen, Karina Standahl; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Guevara, Marcela; Sund, Malin; Bodén, Stina; Gunter, Marc J.; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Aguilera-Buenosvinos, Inmaculada; Tsilidis, Kostas K.; Heath, Alicia K.; Aune, Dagfinn; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
      Background - The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.<p> <p>Methods - A total of 13,270 incident breast ...
    • Associations between dietary inflammatory scores and biomarkers of inflammation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Viallon, Vivian; Artaud, Fanny; Hébert, James R.; Shivappa, Nitin; Agudo, Antonio; Tjønneland, Anne; Mellemkjær, Lene; Kaaks, Rudolf; Katzke, Verena A.; Schulze, Matthias B.; Frenoy, Pauline; Mancini, Francesca Romana; De Magistris, Maria Santucci; Macciotta, Alessandra; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Chirlaque, María-Dolores; Petrova, Dafina; Castro-Espin, Carlota; Quirós, J. Ramón; Guevara, Marcela; Amiano, Pilar; Borné, Yan; Sandström, Maria; Nilsson, Lena Maria; Heath, Alicia K.; Mayen, Ana-Lucia; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Dossus, Laure; Rinaldi, Sabina; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-17)
      Background - Since the first version of the dietary inflammatory index (DII®) developed in the past decade, several other versions have been developed. However, to date no study has attempted to compare these versions with respect to their associations with biomarkers of inflammation.<p> <p>Objective - We aimed to investigate the relationship between four dietary inflammatory scores [DII, two ...
    • Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort 

      Allione, Alessandra; Viberti, Clara; Cotellessa, Ilaria; Catalano, Chiara; Casalone, Elisabetta; Cugliari, Giovanni; Russo, Alessia; Guarrera, Simonetta; Mirabelli, Dario; Sacerdote, Carlotta; Gentile, Marco; Eichelmann, Fabian; Schulze, Matthias B.; Harlid, Sophia; Eriksen, Anne Kirstine; Tjønneland, Anne; Andersson, Martin; Dollé, Martijn E.T.; Van Puyvelde, Heleen; Weiderpass, Elisabete; Rodriguez-Barranco, Miguel; Agudo, Antonio; Heath, Alicia K.; Chirlaque, María-Dolores; Truong, Thérèse; Dragic, Dzevka; Severi, Gianluca; Sieri, Sabina; Sandanger, Torkjel M; Ardanaz, Eva; Vineis, Paolo; Matullo, Giuseppe (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)
      Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer mainly caused by asbestos exposure. Specific and sensitive noninvasive biomarkers may facilitate and enhance screening programs for the early detection of cancer. We investigated DNA methylation (DNAm) profiles in MPM prediagnostic blood samples in a case-control study nested in the European Prospective Investigation into Cancer ...
    • Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer 

      Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, Curtis; Hallberg, Emily; Agata, Simona; Ahsan, Habibul; Aittomäki, Kristiina; Ambrosone, Christine; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Arun, Banu K.; Arver, Brita; Barile, Monica; Barkardottir, Rosa; Barrowdale, Daniel; Beckmann, Lars; Beckmann, Matthias W.; Benitez, Javier; Blank, Stephanie V.; Blomqvist, Carl; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Bonanni, Bernardo; Brauch, Hiltrud; Brenner, Hermann; Burwinkel, Barbara; Buys, Saundra S.; Caldes, Trinidad; Caligo, Maria A.; Canzian, Federico; Carpenter, Jane; Chang-Claude, Jenny; Chanock, Stephen J.; Chung, Wendy K.; Claes, Kathleen B.M.; Cox, Angela; Cross, Simon S.; Cunningham, Julie M.; Czene, Kamila; Daly, Mary B.; Damiola, Francesca; Darabi, Hatef; De La Hoya, Miguel; Devilee, Peter; Diez, Orland; Ding, Yuan C.; Dolcetti, Riccardo; Domchek, Susan M.; Dorfling, Cecilia M.; Dos-Santos-Silva, Isabel; Dumont, Martine; Dunning, Alison M; Eccles, Diana M; Ehrencrona, Hans; Ekici, Arif B; Eliassen, Heather; Ellis, Steve; Fasching, Peter A; Figueroa, Jonine; Flesch-Janys, Dieter; Försti, Asta; Fostira, Florentia; Foulkes, William D; Friebel, Tara; Friedman, Eitan; Frost, Debra; Gabrielson, Marike; Gammon, Marilie D; Ganz, Patricia A; Gapstur, Susan M; Garber, Judy; Gaudet, Mia M; Gayther, Simon A; Gerdes, Anne-Marie; Ghoussaini, Maya; Giles, Graham G; Glendon, Gord; Godwin, Andrew K; Goldberg, Mark S; Goldgar, David E; Gonzalez-Neira, Anna; Greene, Mark H; Gronwald, Jacek; Guenel, Pascal; Gunter, Marc; Haeberle, Lothar; Haiman, Christopher A; Hamann, Ute; Hansen, Thomas V O; Hart, Steven; Healey, Sue; Heikkinen, Tuomas; Henderson, Brian E; Herzog, Josef; Hogervorst, Frans B L; Hollestelle, Antoinette; Hooning, Maartje J; Hoover, Robert N; Hopper, John L; Humphreys, Keith; Hunter, David J; Huzarski, Tomasz; Imyanitov, Evgeny N; Isaacs, Claudine; Jakubowska, Anna; James, Paul; Janavicius, Ramunas; Jensen, Uffe Birk; John, Esther M; Jones, Michael; Kabisch, Maria; Kar, Siddhartha; Karlan, Beth Y; Khan, Sofia; Khaw, Kay-Tee; Kibriya, Muhammad G; Knight, Julia A; Ko, Yon-Dschun; Konstantopoulou, Irene; Kosma, Veli-Matti; Kristensen, Vessela N.; Kwong, Ava; Laitman, Yael; Lambrechts, Diether; Lazaro, Conxi; Lee, Eunjung; Le Marchand, Loic; Lester, Jenny; Lindblom, Annika; Lindor, Noralane; Lindstrom, Sara; Liu, Jianjun; Long, Jirong; Lubinski, Jan; Mai, Phuong L; Makalic, Enes; Malone, Kathleen E; Mannermaa, Arto; Manoukian, Siranoush; Margolin, Sara; Marme, Frederik; Martens, John W M; Mcguffog, Lesley; Meindl, Alfons; Miller, Austin; Milne, Roger L; Miron, Penelope; Montagna, Marco; Mazoyer, Sylvie; Mulligan, Anna M; Muranen, Taru A; Nathanson, Katherine L; Neuhausen, Susan L; Nevanlinna, Heli; Nordestgaard, Børge G; Nussbaum, Robert L; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I; Olson, Janet E; Osorio, Ana; Park, Sue K; Peeters, Petra H; Peissel, Bernard; Peterlongo, Paolo; Peto, Julian; Phelan, Catherine M; Pilarski, Robert; Poppe, Bruce; Pylkäs, Katri; Radice, Paolo; Rahman, Nazneen; Rantala, Johanna; Rappaport, Christine; Rennert, Gad; Richardson, Andrea; Robson, Mark; Romieu, Isabelle; Rudolph, Anja; Rutgers, Emiel J; Sanchez, Maria-Jose; Santella, Regina M; Sawyer, Elinor J; Schmidt, Daniel F; Schmidt, Marjanka K; Schmutzler, Rita K; Schumacher, Fredrick; Scott, Rodney; Senter, Leigha; Sharma, Priyanka; Simard, Jacques; Singer, Christian F; Sinilnikova, Olga M; Soucy, Penny; Southey, Melissa; Steinemann, Doris; Stenmark-Askmalm, Marie; Stoppa-Lyonnet, Dominique; Swerdlow, Anthony; Szabo, Csilla I; Tamimi, Rulla; Tapper, William; Teixeira, Manuel R; Teo, Soo-Hwang; Terry, Mary B; Thomassen, Mads; Thompson, Deborah; Tihomirova, Laima; Toland, Amanda E; Tollenaar, Robert A E M; Tomlinson, Ian; Truong, Thérèse; Tsimiklis, Helen; Teulé, Alex; Tumino, Rosario; Tung, Nadine; Turnbull, Clare; Ursin, Giske; Van Deurzen, Carolien H M; Van Rensburg, Elizabeth J; Varon-Mateeva, Raymonda; Wang, Zhaoming; Wang-Gohrke, Shan; Weiderpass, Elisabete; Weitzel, Jeffrey N; Whittemore, Alice; Wildiers, Hans; Winqvist, Robert; Yang, Xiaohong R; Yannoukakos, Drakoulis; Yao, Song; Zamora, M Pilar; Zheng, Wei; Hall, Per; Kraft, Peter; Vachon, Celine; Slager, Susan; Chenevix-Trench, Georgia; Pharoah, Paul D P; Monteiro, Alvaro A N; Garcia-Closas, Montserrat; Easton, Douglas F; Antoniou, Antonis C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-27)
      Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10−8) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative ...
    • The impact of coding germline variants on contralateral breast cancer risk and survival 

      Morra, Anna; Mavaddat, Nasim; Muranen, Taru A.; Ahearn, Thomas U.; Allen, Jamie; Andrulis, Irene L.; Auvinen, Päivi; Becher, Heiko; Behrens, Sabine; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Brauch, Hiltrud; Camp, Nicola J.; Carvalho, Sara; Castelao, Jose E.; Cessna, Melissa H.; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Sahlberg, Guro Kristine Kleivi; Børresen-Dale, Anne-Lise; Gram, Inger Torhild; Olsen, Karina Standahl; Engebråten, Olav; Naume, Bjørn; Geisler, Jürgen; Grenaker, Grethe Irene; Czene, Kamila; Decker, Brennan; Dennis, Joe; Dörk, Thilo; Dorling, Leila; Dunning, Alison M.; Ekici, Arif B.; Eriksson, Mikael; Evans, D. Gareth; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; Gago-Dominguez, Manuela; García-Closas, Montserrat; Geurts-Giele, Willemina R.R.; Giles, Graham G.; Guénel, Pascal; Gündert, Melanie; Hahnen, Eric; Hall, Per; Hamann, Ute; Harrington, Patricia A.; He, Wei; Heikkilä, Päivi; Hooning, Maartje J.; Hoppe, Reiner; Howell, Anthony; Humphreys, Keith; Kristensen, Vessela N.; Mannermaa, Arto; Manoochehri, Mehdi; Manoukian, Siranoush; Margolin, Sara; Mavroudis, Dimitrios; Milne, Roger L.; Mulligan, Anna Marie; Newman, William G.; Park-Simon, Tjoung-Won; Peterlongo, Paolo; Pharoah, Paul D.P.; Rhenius, Valerie; Saloustros, Emmanouil; Sawyer, Elinor J.; Schmutzler, Rita K.; Shah, Mitul; Spurdle, Amanda B.; Tomlinson, Ian; Truong, Thérèse; van Veen, Elke M.; Vreeswijk, Maaike P.G.; Wang, Qin; Wendt, Camilla; Yang, Xiaohong R.; Nevanlinna, Heli; Devilee, Peter; Easton, Douglas F.; Schmidt, Marjanka K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contralateral breast cancer (CBC) risk and breast cancer-specific survival (BCSS) is scarce. The aim of this study was to assess the association of protein-truncating variants (PTVs) and rare missense variants (MSVs) in nine known (ATM, BARD1, BRCA1, BRCA2, CHEK2, PALB2, RAD51C, ...
    • Inflammatory potential of the diet and association with risk of differentiated thyroid cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Dossus, Laure; Shivappa, Nitin; Hébert, James R.; Agudo, Antonio; Tjonneland, Anne; Halkjaer, Jytte; Overvad, Kim; Katzke, Verena A.; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Dragna, Luca; Iannuzzo, Gabriella; Jensen, Torill Miriam Enget; Brustad, Magritt; Skeie, Guri; Zamora-Ros, Raul; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María-Dolores; Ardanaz, Eva; Almquist, Martin; Sonestedt, Emily; Sandström, Maria; Nilsson, Lena Maria; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina; Boutron-Ruault, Marie-Christine; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
      Purpose - Chronic inflammation is thought to initiate or promote differentiated thyroid cancer (DTC) and previous studies have shown that diet can modulate this inflammatory process. We aimed to evaluate the association of several dietary scores reflecting the inflammatory potential of the diet with DTC risk.<p> <p>Methods - Within the EPIC cohort, 450,063 participants were followed during a mean ...