• Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers 

      Grindedal, Eli Marie; Heramb, Cecilie; Karsrud, Inga; Ariansen, Sarah Louise; Mæhle, Lovise Olaug; Undlien, Dag Erik; Norum, Jan; Schlichting, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-21)
      Background: <br> Identification of BRCA mutations in breast cancer (BC) patients influences treatment and survival and may be of importance for their relatives. Testing is often restricted to women fulfilling high-risk criteria. However, there is limited knowledge of the sensitivity of such a strategy, and of the clinical aspects of BC caused by BRCA mutations in less selected BC cohorts. The aim ...