• Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants 

      Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Pedersen, Tanja; Andresen, Jannicke Hanne; Rettedal, Siren; Støen, Ragnhild; Nakstad, Britt; Willassen, Nils Peder; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-16)
      <i>Objectives</i>: In 2014 probiotic supplementation (<i>Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis;</i> Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic therapy on the developing gut microbiota and antibiotic resistome in ...
    • The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay 

      Hjerde, Erik; Holden, Matthew TG; Seeger, Kathy; Lorentzen, Marit Sjo; Bason, Nathalie; Paulsen, Steinar; Willassen, Nils Peder; Churcher, Carol; Harris, David; Norbertczak, Halina; Quail, Michael A; Sanders, Suzanne; Thurston, Scott; Parkhill, Julian; Thomson, Nicholas R (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-12-19)
      <b>Background:</b> The fish pathogen Aliivibrio salmonicida is the causative agent of cold-water vibriosis in marine aquaculture. The Gram-negative bacterium causes tissue degradation, hemolysis and sepsis in vivo.<BR><BR> <b>Results:</b> In total, 4 286 protein coding sequences were identified, and the 4.6 Mb genome of A. salmonicida has a six partite architecture with two chromosomes and four ...