Blar i forfatter Det helsevitenskapelige fakultet "Winberg, J.-O."

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    • The TNF Receptors p55 and p75 Mediate Chemotaxis of PMN Induced by TNFα and a TNFα 36–62 Peptide 

      Rekdal, Ø.; Espevik, T.; Konopski, Z.; Svendsen, J. S.; Winberg, J.-O.; Østerud, B. (Journal article; Tidsskriftartikkel; Peer reviewed, 1994)
      The present study was performed to examine whether residues 36–62 of TNFα contain the chemotactic domain of TNFα, and whether the p55 and p75 TNF receptors are involved in TNFα induced chemotaxis. The chemotactic effect of TNFα on PMN was inhibited by the mAbs Hrt-7b and Utr-1, against the p55 and p75 TNF receptors, respectively. Both receptors may therefore be required for mediating the chemotactic ...