• Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing 

      Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M. A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J. K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, W. M. Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher; Levy, Renata Bertazzi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, ...
    • Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition 

      Wedekind, Roland; Rothwell, Joseph A.; Viallon, Vivian; Keski-Rahkonen, Pekka; Schmidt, Julie A.; Chajes, Veronique; Katzke, Vna; Johnson, Theron; Santucci de Magistris, Maria; Krogh, Vittorio; Amiano, Pilar; Sacerdote, Carlotta; Redondo-Sánchez, Daniel; Huerta, José María; Tjønneland, Anne; Pokharel, Pratik; Jakszyn, Paula; Tumino, Rosario; Ardanaz, Eva; Sandanger, Torkjel M; Winkvist, Anna; Hultdin, Johan; Schulze, Matthias B.; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-08)
      Background & aims: Circulating levels of acylcarnitines (ACs) have been associated with the risk of various diseases such as cancer and type 2 diabetes. Diet and lifestyle factors have been shown to influence AC concentrations but a better understanding of their biological, lifestyle and metabolic determinants is needed. <p><p>Methods: Circulating ACs were measured in blood by targeted (15 ACs) and ...
    • Isocaloric substitution of carbohydrates with protein: The association with weight change and mortality among patients with type 2 diabetes 

      Campmans-Kuijpers, Marjo J.E.; Sluijs, Ivonne; Nöthlings, Ute; Freisling, Heinz; Overvad, Kim; Weiderpass, Elisabete; Fagherazzi, Guy; Kühn, Tilman; Katzke, Verena A.; Mattiello, Amalia; Sonestedt, Emily; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Spijkerman, Annemieke M.W.; Barricarte, Aurelio; Ricceri, Fulvio; Chamosa, Saioa; Johansson, Ingegerd; Winkvist, Anna; Tjønneland, Anne; Sluik, Diewertje; Boeing, Heiner; Beulens, Joline W.J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-18)
      Background: The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD) mortality risk in patients with type 2 diabetes. <p>Methods: The study ...
    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...
    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study 

      Moskal, Aurelie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T.; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina E N; Dahm, Christina C; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Kuhn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H; Bueno-de-Mesquita, Bas H; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José María Huerta; Quirós, José R.; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay-Tee; Huybrechts, Inge; Tsilidis, Konstantinos K; Ward, Heather; Gunter, Marc J; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)
      Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/ nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. <p>Methods: Among 477 312 participants, ...
    • Meal patterns across ten European countries - Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study 

      Huseinovic, Ena; Winkvist, Anna; Slimani, Nadia; Park, Mi-Kyung; Freisling, Heinz; Boeing, Heiner; Buckland, Genevieve; Schwingshackl, Lukas; Weiderpass, Elisabete; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Katzke, Verena A.; Kühn, Tilman; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Pala, Valeria; Palli, Domenico; Ricceri, Fulvio; Santucci de Magistris, Maria; Tumino, Rosaria; Engeset, Dagrun; Enget, Torill; Skeie, Guri; Barricarte, Aurelio; Bonet, Catalina Bonet; Chirlaque, María-Dolores; Amiano, Pilar; Quirós, José Ramón; Sánchez, Mariá-José; Dias, Joana A.; Drake, Isabel; Wennberg, Maria; Boer, Jolanda M.A.; Ocké, Marga C.; Verschuren, W.M. Monique; Lassale, Camille M.; Perez-Cornago, Aurora; Riboli, Élio B.; Ward, Heather A.; Forslund, Heléne Bertéus (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-19)
      Objective: To characterize meal patterns across ten European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study. Design: Cross-sectional study utilizing dietary data collected through a standardized 24 h diet recall during 1995–2000. Eleven predefined intake occasions across a 24 h period were assessed during the interview. In ...
    • Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study 

      Freisling, Heinz; Noh, Hwayoung; Slimani, Nadia; Chajès, Véronique; May, Anne M.; Peeters, Petra H; Weiderpass, Elisabete; Cross, Amanda J.; Skeie, Guri; Jenab, Mazda; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Katzke, Verena A.; Kühn, Tilman; Steffen, Annika; Boeing, Heiner; Tjønneland, Anne; Kyrø, Cecilie; Hansen, Camilla P.; Overvad, Kim; Duell, Eric J.; Redondo-Sánchez, Daniel; Amiano, Pilar; Navarro, Carmen; Barricarte, Aurelio; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Aune, Dagfinn; Ward, Heather; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Berrino, Franco; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Bueno-De-Mesquita, Hendrik Bastiaan; Ericson, Ulrika; Sonestedt, Emily; Winkvist, Anna; Braaten, Tonje; Romieu, Isabelle; Sabaté, Joan (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-07-21)
      <p><i>Purpose</i>: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.</p> <p><i>Methods</i>: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European ...
    • Nutrient patterns and their food sources in an international study setting: Report from the EPIC study 

      Moskal, Aurelie; Pisa, Pedro T; Ferrari, Pietro; Byrnes, Graham; Freisling, Heinz; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Nailler, Laura; Wendt, Andrea; Kühn, Tilman; Boeing, Heiner; Buijsse, Brian; Tjønneland, Anne; Halkjær, Jytte; Dahm, Christina C; Chiuve, Stephanie E; Quirós, Jose R; Buckland, Genevieve; Molina-Montes, Esther; Amiano, Pilar; Huerta Castaño, José M; Gurrea, Aurelio Barricarte; Khaw, Kay-Tee; Lentjes, Marleen A; Key, Timothy J; Romaguera, Dora; Vergnaud, Anne-Claire; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Sacerdote, Carlotta; De Magistris, Maria Santucci; Bueno-de-Mesquita, H Bas; Ocké, Marga C; Beulens, Joline W J; Ericson, Ulrika; Drake, Isabel; Nilsson, Lena M; Winkvist, Anna; Weiderpass, Elisabete; Hjartåker, Anette; Riboli, Elio; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...
    • Plasma elaidic acid level as biomarker of industrial trans fatty acids and risk of weight change: Report from the EPIC study 

      Chajès, Véronique; Biessy, Carine; Ferrari, Pietro; Romieu, Isabelle; Freisling, Heinz; Huybrechts, Inge; Scalbert, Augustin; Bueno-de-Mesquita, H. Bas; Romaguera, Dora; Gunter, Mark J.; Vineis, Paolo; Hansen, Camilla Plambeck; Jakobsen, Marianne Uhre; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Katzke, Verana; Neamat-Allah, Jasmine; Boeing, Heiner; Bachlechner, Ursula; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Pala, Valeria; Masala, Giovanna; Mattiello, Amalia; Skeie, Guri; Weiderpass, Elisabete; Agudo, Antonio; Huerta, José María; Sánchez, Mariá-José; Dorronsoro, Miren; Quirós, José Ramón; Johansson, Ingegerd; Winkvist, Anna; Sonested, Emily; Key, Timothy J.; Khaw, Kay-Tee; Wareham, Nicholas J.; Peeters, Petra H.M.; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-12)
      Background Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition ...
    • Timing of eating across ten European countries - Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study 

      Huseinovic, Ena; Winkvist, Anna; Freisling, Heinz; Slimani, Nadia; Boeing, Heiner; Buckland, Genevieve; Schwingshackl, Lukas; Olsen, Anja; Tjønneland, Anne; Stepien, Magdalena; Boutron-Ruault, Marie-Christine; Mancini, Francesca; Artaud, Fanny; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Tumino, Rosario; Masala, Giovanna; Krogh, Vittorio; Santucci De Magistris, Maria; Ocké, Marga C.; Brustad, Magritt; Enget Jensen, Torill; Skeie, Guri; Rodriguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Quirós, José Ramón; Jakszyn, Paula; Sonestedt, Emily; Ericson, Ulrika; Wennberg, Maria; Key, Timothy J.; Aune, Dagfinn; Riboli, Elio; Weiderpass, Elisabete; Berteus Forslund, Helene (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-17)
      <p><i>Objective</i>: To examine timing of eating across ten European countries.</p> <p><i>Design</i>: Cross-sectional analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study using standardized 24 h diet recalls collected during 1995–2000. Eleven predefined food consumption occasions were assessed during the recall interview. We present time of consumption ...
    • A traditional Sami diet score as a determinant of mortality in a general northern Swedish population 

      Nilsson, Lena Maria; Winkvist, Anna; Brustad, Magritt; Jansson, Jan-Håkan; Johansson, Ingegerd; Lenner, Per; Lindahl, Bernt; Van Guelpen, Bethany (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-04)
      Objectives. To examine the relationship between ‘‘traditional Sami’’ dietary pattern and mortality in a general northern Swedish population. Study design. Population-based cohort study.<p> <p>Methods. We examined 77,319 subjects from the Va¨sterbotten Intervention Program (VIP) cohort. A traditional Sami diet score was constructed by adding 1 point for intake above the median level of red meat, ...
    • A treelet transform analysis to relate nutrient patterns to the risk of hormonal receptor-defined breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Assi, Nada; Moskal, Aurelie; Slimani, Nadia; Viallon, Vivian; Chajes, Veronique; Freisling, Heinz; Monni, Stefano; Knueppel, Sven; Förster, Jana; Weiderpass, Elisabete; Lujan-Barroso, Leila; Amiano, Pilar; Ardanaz, Eva; Molina-Montes, Esther; Salmeron, Diego; Quiros, Jose Ramon; Olsen, Anja; Tjonneland, Anne; Dahm, Christina C; Overvad, Kim; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Fortner, Renee Turzanski; Kaaks, Rudolf; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; de Magistris, Maria Santucci; Masala, Giovanna; Agnoli, Claudia; Ricceri, Fulvio; Tumino, Rosario; Bueno De Mesquita, H Bas; Bakker, Marije F; Peeters, Petra HM; Skeie, Guri; Braaten, Tonje; Winkvist, Anna; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nicholas J; Key, Tim; Travis, Ruth; Schmidt, Julie A; Merritt, Melissa A; Riboli, Elio; Romieu, Isabelle; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-23)
      Objective: Pattern analysis has emerged as a tool to depict the role of multiple nutrients/foods in relation to health outcomes. The present study aimed at extracting nutrient patterns with respect to breast cancer (BC) aetiology.<br> Design: Nutrient patterns were derived with treelet transform (TT) and related to BC risk. TT was applied to twenty-three log-transformed nutrient densities ...