Now showing items 1-6 of 6
Combined impact of healthy lifestyle factors on colorectal cancer: A large European cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. Methods Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, number of children, age at first and last pregnancies, time since last full-term ...
Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-02)
Background:<br>Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.<br>Methods:<br>A nested ...
Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-22)
Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of ...
Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: A nested case-control study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-04)
Background:<br>Leakage of bacterial products across the gut barrier may play a role in liver diseases which often precede the development of liver cancer. However, human studies, particularly from prospective settings, are lacking.<br>Methods:<br>We used a case-control study design nested within a large prospective cohort to assess the association between circulating levels of anti-lipopolysaccharide ...
Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...