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Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-20)
Background: Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. <br>Methods: We evaluated cross-sectional relationships between lifestyle and reproductive factors and these markers among controls ( n = 1910) from a nested case-control study in the European Prospective Investigation into Cancer and Nutrition ...
Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-18)
<p><i>Background</i>: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential ...