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Basal‐like breast cancer engages tumor‐supportive macrophages via secreted factors induced by extracellular S100A4
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-09)
The tumor microenvironment (TME) may influence both cancer progression and therapeutic response. In breast cancer, particularly in the aggressive triple‐negative/basal‐like subgroup, patient outcome is strongly associated with the tumor's inflammatory profile. Tumor‐associated macrophages (TAMs) are among the most abundant immune cells in the TME, shown to be linked to poor prognosis and therapeutic ...