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Drug permeability profiling using cell-free permeation tools: Overview and applications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-13)
Cell-free permeation systems are gaining interest in drug discovery and development as tools to obtain a reliable prediction of passive intestinal absorption without the disadvantages associated with cell- or tissue-based permeability profiling. Depending on the composition of the barrier, cell-free permeation systems are classified into two classes including (i) biomimetic barriers which are ...