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Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-15)
Background: <br>A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral
bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose
course of antibiotics had a better effect than placebo at 12 months’ follow-up. The present study examines the effects
of antibiotic treatment in chronic LBP patients with ...
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-16)
<p><i>Objective - </i>To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes).
<p><i>Design - </i>Double blind, parallel group, placebo controlled, multicentre trial.
<p><i>Setting - </i>Hospital outpatient clinics at six hospitals in Norway.
<p><i>Participants ...