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Isocaloric substitution of carbohydrates with protein: The association with weight change and mortality among patients with type 2 diabetes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-18)
Background: The health impact of dietary replacement of carbohydrates with protein for patients with type 2
diabetes is still debated. This study aimed to investigate the association between dietary substitution of
carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD)
mortality risk in patients with type 2 diabetes.
<p>Methods: The study ...
Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
<i>Background</i>
- Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, ...
Association between anthropometry and lifestyle factors and risk of B-cell lymphoma: An exposome-wide analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-31)
To better understand the role of individual and lifestyle factors in human disease, an exposome‐wide association study was performed to investigate within a single‐study anthropometry measures and lifestyle factors previously associated with B‐cell lymphoma (BCL). Within the European Prospective Investigation into Cancer and nutrition study, 2402 incident BCL cases were diagnosed from 475 426 ...
Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-25)
Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the
risk of colorectal cancer (CRC) development. We examined the association between CRC risk and
genotype for single nucleotide polymorphisms (SNPs) in selenoprotein and Se metabolic pathway
genes. <i>Illumina Goldengate</i> assays were designed and resulted in the genotyping of 1040 variants
in 154 genes ...
A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p>
<p>Methods - The association ...
Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study
(Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-07-21)
<p><i>Purpose</i>: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.</p>
<p><i>Methods</i>: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European ...
Prediagnostic Blood Selenium Status and Mortality among Patients with Colorectal Cancer in Western European Populations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
A higher selenium (Se) status has been shown to be associated with lower risk for colorectal
cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The
associations of prediagnostic circulating Se status (as indicated by serum Se and selenoprotein P
(SELENOP) measurements) with overall and CRC-specific mortality were estimated using multivariable Cox proportional ...
Pre-diagnostic circulating insulin-like growth factor-I and bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-04)
Previous <i>in vitro</i> and case–control studies have found an association between the insulin‐like growth factor (IGF)‐axis and bladder cancer risk. Circulating concentrations of IGF‐I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre‐diagnostic circulating IGF‐I concentrations and bladder cancer has never been studied ...
Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-10)
Background: Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their
association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025
invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included
521 330 total ...
Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-11)