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Osteoprotegerin and breast cancer risk by hormone receptor subtype: A nested case-control study in the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-08)
Background:<br>Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role as the decoy receptor for both the RANK ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Circulating OPG and breast cancer risk has been examined in only one prior study.<br>Methods:<br>A case-control ...
Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and
progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer
are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited
385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...
Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-05)
The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.
Methods The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs. ...
Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
Background: Results from several cohort and case–control studies suggest a protective association between current alcohol
intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain
unanswered.<p>
<p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid
carcinoma ...
Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk: Results from the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-03)
A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic transformation after sexually transmitted infections (STI) and pelvic inflammatory disease. We investigated the hypothesis that past STI infection, particularly Chlamydia trachomatis, is associated with higher EOC ...
Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the Pan-European EPIC Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
<i>Background</i>
- There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition).<P><P>
<i>Methods</i>
- In this prospective study of 409 885 men and women in 9 European countries, diet ...