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Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: A nested case-control study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-04)
Background:<br>Leakage of bacterial products across the gut barrier may play a role in liver diseases which often precede the development of liver cancer. However, human studies, particularly from prospective settings, are lacking.<br>Methods:<br>We used a case-control study design nested within a large prospective cohort to assess the association between circulating levels of anti-lipopolysaccharide ...
Combined impact of healthy lifestyle factors on colorectal cancer: A large European cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...
Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-10)
Background: Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their
association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025
invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included
521 330 total ...
Circulating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)
Background: Infammation has been hypothesized to play a role in the development and progression of breast can‑
cer and might diferently impact breast cancer risk among pre and postmenopausal women. We performed a nested
case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive
protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...
Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background
The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain.
Methods
Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, number of children, age at first and last pregnancies, time since last full-term ...