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Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-23)
<i>Background</i> - The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex diseases.<p>
<p><i>Objectives</i> - First, to summarize the main design features of a prospective case-control study –nested within the European Prospective Investigation ...
Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-17)
<p><i>Background</i>: Leukocyte telomere length (LTL) and mitochondrial genome (mtDNA) copy number and deletions have been proposed as risk markers for various cancer types, including breast cancer (BC).</p>
<p><i>Methods</i>: To gain a more comprehensive picture on how these markers can modulate BC risk, alone or in conjunction, we performed simultaneous measurements of LTL and mtDNA copy number ...