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Evaluation of the medical student research programme in Norwegian medical schools : a survey of students and supervisors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-14)
Background: The Medical Student Research Programme is a national education and grant scheme for medical students who wish to carry out research in parallel with their studies. The purpose of the programme is to increase recruitment of people with a standard medical degree to medical research. The Research Programme was established in 2002 and underwent a thorough evaluation during the spring of ...
Asialoglycoprotein Receptor (ASGP-R) is Liver Parenchymal Cells is Involved in Elimination of Recombinant Human TFPI
(Preprint; Manuskript; Peer reviewed, 2010)
We here report on a study carried out to determine the early clearance kinetics, and organ, cell(s) and receptor(s) responsible for the clearance of full length TFPI purified from BHK cells (TFPI<sup>BHK</sup>). Following intravenous administration, <sup>125</sup>I-TFPI<sup>BHK</sup> was cleared with a biphasic elimination curve, and with a significantly slower t<sub>1/2</sub>α compared to recombinant ...
Effect of Unfractionated Heparin on TFPI Elimination
(Preprint; Manuskript; Peer reviewed, 2010)
Background: Tissue factor pathway inhibitor (TFPI) plays an important role for the anticoagulant effect of heparin. Depletion of intravascular TFPI by treatment with unfractionated heparin (UFH), and not by low molecular weight heparin (LMWH), has been suggested to explain the superiority of LMWH in treatment of both arterial and venous thrombosis. The present study was undertaken to investigate ...
Physical activity and risk of venous thromboembolism. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
Existing data sources in clinical epidemiology: The Scandinavian Thrombosis and Cancer Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-16)
Background: Although venous thromboembolism (VTE) is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian Thrombosis and Cancer (STAC) Cohort was established by merging individual data from three large Scandinavian cohorts (The Tromsø Study, the second Nord-Trøndelag Health Study, ...
Atrial fibrillation and future risk of venous thromboembolism:the Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Thyroid function, as assessed by TSH, and future risk of venous thromboembolism: The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-21)
Objective: The relationship between thyroid function and the risk of venous thromboembolism (VTE) has not been addressed in population-based cohorts. We investigated the association between TSH levels and the risk of VTE in a general adult population. Design: Population-based cohort study. Methods: TSH was measured in 11 962 subjects aged 25–89 years who participated in Tromsø 4–6 starting in ...
Cystatin C is associated with risk of venous thromboembolism in subjects with normal kidney function - the Tromso study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
Background Previous studies have shown an association between impaired kidney function, assessed by cystatin C-based estimated glomerular filtration rate, and venous thromboembolism. The aim of this study was to investigate whether serum cystatin C was associated with a risk of venous thromboembolism among subjects with normal kidney function in a prospective population-based study. Design and ...
Alcohol consumption, types of alcoholic beverages and risk of Venous Thromboembolism : the Tromsø Study
(Master thesis; Mastergradsoppgave, 2011-11-01)
Moderate alcohol consumption has been shown to protect against cardiovascular diseases. The association between alcohol consumption, especially types of alcoholic beverages, and venous thromboembolism (VTE) is less well described. The aim of this study was to investigate the impact of alcohol consumption and different alcoholic beverages on risk of VTE. Information on alcohol consumption were ...
Impact of incident venous thromboembolism on risk of arterial thrombotic diseases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11-22)
BACKGROUND: Growing evidence supports an association between venous thromboembolism (VTE) and arterial thrombotic diseases (ie, myocardial infarction and ischemic stroke). We aimed to study the association between VTE and future arterial events and to determine the population attributable risk of arterial events by VTE in a large prospective cohort recruited from the general population. METHODS AND ...