Viser treff 1-10 av 60
Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-13)
Introduction: The introduction of high-throughput technologies, also called -omics technologies, into epidemiology has raised the need for high-quality observational studies to reduce several sources of error and bias. Methods: The Norwegian Women and Cancer (NOWAC) postgenome cohort study consists of approximately 50,000 women born between 1943 and 1957 who gave blood samples between 2003 ...
Towards a more functional concept of causality in cancer research.
(Journal article; Tidsskriftartikkel, 2010)
Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-29)
Background: Gonadotropin releasing hormone (GNRH1) triggers the release of follicle stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene encoding GNRH1 or its receptor may influence breast cancer risk by modulating production of ovarian steroid hormones. We studied the association between breast cancer risk and polymorphisms in genes that code for GNRH1 ...
Dairy consumption and calcium intake and risk of breast cancer in a prospective cohort : The Norwegian Women and Cancer study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
A processual model for functional analyses of carcinogenesis in the prospective cohort design
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)
Traditionally, the prospective design has been chosen for risk factor analyses of lifestyle and cancer using mainly estimation by survival analysis methods. With new technologies, epidemiologists can expand their prospective studies to include functional genomics given either as transcriptomics, mRNA and microRNA, or epigenetics in blood or other biological materials. The novel functional analyses ...
What characterises women who eat potatoes? A cross-sectional study among 74,208 women in the Norwegian Women and Cancer cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-19)
<p>Background: Studies of potato consumption have shown that age, region, socioeconomic status, and household structure are important determinants. <p>Objective: This study aims to map which factors influence potato consumption among women in the Norwegian Women and Cancer (NOWAC) study. <p>Design: A cross-sectional study using a postal questionnaire among 74,208 NOWAC participants aged ...
Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-15)
DNA hypomethylation in certain genes is associated with tobacco exposure but it is unknown whether these methylation changes translate into increased lung cancer risk. In an epigenome-wide study of DNA from pre-diagnostic blood samples from 132 case–control pairs in the NOWAC cohort, we observe that the most significant associations with lung cancer risk are for cg05575921 in AHRR (OR for 1 s.d.=0.37, ...
Two hundred years of cancer epidemiology in Norway-before and during the NOFE era
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
Test–retest reliability of self-reported diabetes diagnosis in the Norwegian Women and Cancer Study: A population-based longitudinal study (n = 33,919)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-21)
Objective: Self-reported information from questionnaires is frequently used in epidemiological studies, but few of these studies provide information on the reproducibility of individual items contained in the questionnaire. We studied the test– retest reliability of self-reported diabetes among 33,919 participants in Norwegian Women and Cancer Study. Methods: The test–retest reliability of ...
Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)