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Atrial Fibrillation and Cause-Specific Risks of Pulmonary Embolism and Ischemic Stroke
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-29)
<p><i>Background</i>: Atrial fibrillation (AF) is a well‐established risk factor for ischemic stroke (IS). Emerging evidence also indicates an association between AF and pulmonary embolism (PE). Because IS may potentially mediate the observed risk of PE in AF, we aimed to assess the impact of AF on the cause‐specific risks of PE and IS in a large cohort recruited from the general population.</p>
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Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-12)
<b>Background:</b> <br>
Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic
control in patients with diabetes. Previous genome-wide association studies (GWAS)
have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable
by their likely biological action as erythrocytic (also associated with erythrocyte traits)
or ...
Atrial fibrillation is associated with cognitive decline in stroke-free subjects: the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-28)
Background and purpose:<br>Previous studies have shown associations between atrial fibrillation (AF) and cognitive decline. We investigated this association in a prospective population study, focusing on whether stroke risk factors modulated this association in stroke-free women and men.<br>Methods:<br>We included 4983 participants (57% women) from the fifth survey of the Tromsø Study (Tromsø 5, ...
Sex Differences in the Impact of Body Mass Index on the Risk of Future Atrial Fibrillation: Insights From the Longitudinal Population-Based Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-19)
<p><i>Background</i>: Atrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated.</p>
<p><i>Methods and Results</i>: Data from the fourth survey (1994–1995) of the Tromsø Study (Norway) were used to investigate the association of single‐measurement BMI on future AF ...
Elevated blood pressure is not associated with accelerated glomerular filtration rate decline in the general non-diabetic middle-aged population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-14)
Although hypertension is a risk factor for end-stage renal disease, this complication develops in
only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient
to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated
blood pressure (BP) was associated with accelerated GFR decline in the general population. The
study ...
The relation between birthweight, childhood body mass index, and overweight and obesity in late adolescence: a longitudinal cohort study from Norway, The Tromsø Study, Fit Futures
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-22)
<i>Objectives</i>: Childhood overweight/obesity is associated
with later overweight/obesity. However, the association
between birth weight and later overweight/obesity has not
been established. The aim of this study was to investigate
the relation between both birth weight and childhood body
mass index (BMI), and adolescent overweight/obesity in a
Norwegian population.<p>
<p><i>Methods</i>: ...
Data on gender contrasts in the risk of incident myocardial infarction by age. The Tromsø Study 1979–2012
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-08)
The data presented in this article relate to the research article entitled “Risk of incident myocardial infarction by gender: Interactions with serum lipids, blood pressure and smoking. The Tromsø Study 1979–2012” (Albrektsen et al., 2017) [1]. Data quantify the gender differences in the risk of myocardial infarction (MI) in terms of incidence rate ratios (IRR), in subgroups defined by serum lipids, ...
The impact of changes in leisure time physical activity on changes in cardiovascular risk factors: results from The Finnmark 3 Study and SAMINOR 1, 1987–2003
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-15)
Objective: <br>The aim of this study was to examine the associations between changes in leisure
time physical activity and changes in cardiovascular risk factors over 16 years and whether they
differ between two ethnic groups in Norway.
<br>Methods: <br>Data were extracted from two population-based studies. Altogether, 3671 men and
women participated in both surveys, and 30% reported being of ...
Ovarian hormones and reproductive risk factors for breast cancer in premenopausal women : the Norwegian EBBA-I study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Ovarian hormones, parity and length of ‘menarche-to-first birth’ time interval are known risk factors for breast cancer, yet the associations between 17β-estradiol, progesterone and these reproductive factors remain unclear.
A total of 204 women (25–35 years) who participated in the Norwegian EBBA-I study collected daily saliva samples for one complete menstrual cycle, and filled in a reproductive ...
Episiotomy characteristics and risks for obstetric anal sphincter injuries: a case-control study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
Objectives To investigate the association between the geometrical properties of episiotomy and obstetric anal sphincter injuries (OASIS) because episiotomies angled at 40–60° are associated with fewer OASIS than episiotomies with more acute angles.
Design Case–control study.
Setting University Hospital of North Norway, Tromsø and Nordland Hospital, Bodø, Norway.
Sample Seventy-four women ...