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Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-19)
Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, treatment characteristics, and outcomes following mild and moderate/severe TBI. We performed mixed-effects regression analyses in the prospective multi-center Collaborative ...
Filtered beauty in Oslo and Tokyo: A spatial frequency analysis of facial attractiveness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-14)
Images of European female and male faces were digitally processed to generate spatial frequency (SF) filtered images containing only a narrow band of visual information within the Fourier spectrum. The original unfiltered images and four SF filtered images (low, medium-low, medium-high and high) were then paired in trials that kept constant SF band and face gender and participants made a forced-choice ...
Betydning av tilbakemelding om avvikende FEV1-verdier i Tromsø 7
(Master thesis; Mastergradsoppgave, 2020-02-21)
<p><i>Bakgrunn:</i> Spirometri er en anbefalt undersøkelse for å diagnostisere og undersøke for obstruktiv lungesykdom. Deltakerne i Tromsø 7 som måler en FEV1 < 70 % (grenseverdi på FEV1 < 65 % hos deltakere > 70 år) fikk et informasjonsskriv på spirometriposten med anbefaling å kontakte sin fastlege. Denne informasjonen kan være en stor fordel for deltakeren hvis det kan avdekke risiko for alvorlig ...
Optimized cutoff maternal age for adverse obstetrical outcomes: A multicenter retrospective cohort study in Urban China during 2011 to 2012
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-05)
<p><i>Background: </i>China's two-child policy has led to a trend of aging in pregnancy which was associated with adverse outcomes. This study aimed to identify the clinically cutoff maternal age for adverse obstetric outcomes in China.
<p><i>Methods: </i>This secondary analysis of a multicenter retrospective cohort study included data of childbearing women from 39 hospitals collected in urban China ...
Data on RT-qPCR assay of nuclear progesterone receptors (nPR), membrane progesterone receptors (mPR) and progesterone receptor membrane components (PGRMC) from human uterine endometrial tissue and cancer cells of the uterine cervix
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
A previous investigation showed that the endometrium normalized in women with endometrial hyperplasia after three months treatment with high dose levonorgestrel IUS (intrauterine system). The effect was maintained even if immunohistochemical analyses of the endometrium showed that nuclear progesterone receptors (nPRs) were completely downregulated. These observations indicated that some type of ...
Health warning labels describing snus as less harmful than smoking: effects on perceptions of risk
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-05)
<i>Background</i> - Using snus (Swedish moist snuff) is less harmful than smoking, but health warning labels (HWLs) on snus products do not reflect this relation. There are few studies on the effects of comparative risk information in snus warning labels. The purpose of this experiment is to examine whether risk perceptions differ after exposure to non-comparative vs. comparative risk information ...
NADPH oxidase 2 mediates myocardial oxygen wasting in obesity
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-19)
Obesity and diabetes are independent risk factors for cardiovascular diseases, and they are associated with the development of a specific cardiomyopathy with elevated myocardial oxygen consumption (MVO<sub>2</sub>) and impaired cardiac efficiency. Although the pathophysiology of this cardiomyopathy is multifactorial and complex, reactive oxygen species (ROS) may play an important role. One of the ...
Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-24)
In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ). The NPs are based on chitosan (CS) conjugate polymers synthesized with different amounts of the photosensitizer tetraphenylchlorin (TPC). These TPC–CS NPs have high loading capacity and strong drug retention due to π–π stacking interactions between the ...
Context and general practitioner decision-making - a scoping review of contextual influence on antibiotic prescribing
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-15)
Background - How contextual factors may influence GP decisions in real life practice is poorly understood. The authors have undertaken a scoping review of antibiotic prescribing in primary care, with a focus on the interaction between context and GP decision-making, and what it means for the decisions made.<p>
<p>Method - The authors searched Medline, Embase and Cinahl databases for English ...
Abridged risk information: Effects of warning labels on snus packages
(Doctoral thesis; Doktorgradsavhandling, 2020-02-28)
<i>Background</i> - We screened the sparse literature on how health warnings on snus products affect risk perception and use intentions, and contributed with two experimental studies on the topic.<p>
<p><i> Methods</i> - First, we examined previous studies on health warnings on smokeless tobacco in a systematic review, studied the manipulations in exposure studies, and systematized the outcome ...