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Persistent Organic Pollutants and the Association with Maternal and Infant Thyroid Homeostasis: A Multipollutant Assessment
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01)
Background:<br>Disruption of thyroid homeostasis has been indicated in human studies targeting effects of persistent organic pollutants (POPs). Influence on the maternal thyroid system by POPs is of special interest during pregnancy because such effects could impair infant thyroid homeostasis.<br> Objectives:<br>We investigated the association between POPs and thyroid-stimulating hormone (TSH) ...
Thyroid homeostasis in mother–child pairs in relation to maternal iodine status. The MISA study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-24)
BACKGROUND/OBJECTIVES: Iodine deficiency during pregnancy may influence maternal and foetal thyroid function with the risk of causing neurocognitive and psychomotor deficits in the offspring. The objective of this study was to assess iodine status in pregnant women from Northern Norway and to investigate the influence of iodine status on maternal and infant thyroid function. <br>SUBJECTS/METHODS: ...
Assessing the relationship between perfluoroalkyl substances, thyroid hormones and binding proteins in pregnant women; a longitudinal mixed effects approach
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04)
<p>The mechanisms involved in thyroid homeostasis are complex, and perfluoroalkyl substances (PFASs) have been indicated to interfere at several levels in this endocrine system. Disruption of the maternal thyroid homeostasis during early pregnancy is of particular concern, where subclinical changes in maternal thyroid hormones (THs) may affect embryonic and foetal development.</p> <p>The present ...