Now showing items 1-5 of 5
N-Acetyl-β-D-Glucosaminidase Does Not Enhance Prediction of Cardiovascular or All-Cause Mortality by Albuminuria in a Low-Risk Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-05)
Albuminuria is a well known risk factor for cardiovascular disease and mortality, but focus on renal tubular dysfunction as a potential risk factor is growing also. The association between the urinary activity of N-acetyl-β-D-glucosaminidase (NAG) and cardiovascular risk has been assessed mostly in cross-sectional studies. We studied the cross-sectional associations between urinary NAG and cardiovascular ...
Association between diastolic dysfunction and future atrial fibrillation in the Tromsø Study from 1994 to 2010
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-13)
Objective. To investigate the association between echocardiographic measurements with emphasis on diastolic dysfunction and risk of atrial fibrillation (AF) in a population-based cohort study. Methods. We followed 2406 participants from the Tromsø Study from 1994 to 2010. Left atrial (LA) size and mitral Doppler indices as measured by echocardiography were used for evaluating diastolic dysfunction. ...
Cardiovascular health and the modifiable burden of incident myocardial infarction: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-06)
Background: The American Heart Association has proposed an impact goal for the year 2020 to improve cardiovascular health by 20%. The objectives of the study were to assess the association between the proposed cardiovascular health metric score and incident myocardial infarction (MI) and to estimate the generalized impact fraction (GIF). <p>Methods: The health metric score was derived from ideal ...
Estimated and Measured GFR Associate Differently with Retinal Vasculopathy in the General Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11)
Background/Aims: Estimated GFR (eGFR) is used extensively in epidemiological research. Validations of eGFR have demonstrated acceptable performance, but the dependence of creatinine and cystatin C on non-GFR factors could confound associations with disease. Few studies have investigated this issue in direct comparison with measured GFR (mGFR). We compared the associations between eGFR and mGFR ...
Genetic variations in the Vitamin D receptor predict type 2 diabetes and myocardial infarction in a community-based population: The tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-23)
Background Though the associations between low serum 25-hydroxyvitamin D (25(OH)D) levels and health outcomes such as type 2 diabetes (T2D), myocardial infarction (MI), cancer, and mortality are well-studied, the effect of supplementation with vitamin D is uncertain. This may be related to genetic differences. Thus, rs7968585, a single nucleotide polymorphism (SNP) of the vitamin D receptor ...