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Ovarian hormones and reproductive risk factors for breast cancer in premenopausal women : the Norwegian EBBA-I study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Ovarian hormones, parity and length of ‘menarche-to-first birth’ time interval are known risk factors for breast cancer, yet the associations between 17β-estradiol, progesterone and these reproductive factors remain unclear.
A total of 204 women (25–35 years) who participated in the Norwegian EBBA-I study collected daily saliva samples for one complete menstrual cycle, and filled in a reproductive ...
Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-07)
Background: Single nucleotide polymorphisms (SNPs) involved in the estrogen pathway and SNPs in the estrogen
receptor alpha gene (ESR1 6q25) have been linked to breast cancer development, and mammographic density is an
established breast cancer risk factor. Whether there is an association between daily estradiol levels, SNPs in ESR1
and premenopausal mammographic density phenotypes is unknown.
Methods: ...
Genetic Polymorphism CYP17 rs2486758 and Metabolic Risk Factors Predict Daily Salivary 17 beta-Estradiol Concentration in Healthy Premenopausal Norwegian Women. The EBBA-I Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-03-14)
Context: The relationship between low-penetrance genes, metabolic risk factors, and levels of endogenous 17β-estradiol and progesterone, which play a role in breast cancer risk, remains unclear.
<br>Objective: The aim of this study was to determine whether common polymorphisms in CYP17, in combination with metabolic risk factors (individually or clustered), alter salivary concentrations of free ...
Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)
Alcohol consumption, endogenous estrogen and mammographic density among premenopausal women
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
Introduction: Alcohol consumption may promote aromatization of androgens to estrogens, which may partly
explain the observations linking alcohol consumption to higher breast cancer risk. Whether alcohol consumption is
associated with endogenous estrogen levels, and mammographic density phenotypes in premenopausal women
remains unclear.<p>
<p>Methods: Alcohol consumption was collected by self-report ...