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Atrial Fibrillation and Cause-Specific Risks of Pulmonary Embolism and Ischemic Stroke
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-29)
<p><i>Background</i>: Atrial fibrillation (AF) is a well‐established risk factor for ischemic stroke (IS). Emerging evidence also indicates an association between AF and pulmonary embolism (PE). Because IS may potentially mediate the observed risk of PE in AF, we aimed to assess the impact of AF on the cause‐specific risks of PE and IS in a large cohort recruited from the general population.</p>
...
Regular physical activity and risk of venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-05)
Venous thromboembolism (VTE) is a complex multifactorial disease that represents a growing public health concern. Identification of modifiable risk factors at the population level may provide a measure to reduce the burden of VTE. In this review, we summarize current knowledge of the role of physical activity on the risk of VTE and VTE-related complications. We also discuss methodological challenges ...
Acute infection as a trigger for incident venous thromboembolism: Results from a population- based case- crossover study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-21)
Background:<br>
A bidirectional relation exists between acute infection and immobilization, and both are triggers for venous thromboembolism (VTE). To what extent the association between infection and VTE‐risk is explained by immobilization is unknown.
<br>Aims:<br>
To investigate the impact of hospitalization with acute infection on the VTE‐risk in patients with and without concomitant ...
Time trends in incidence rates of venous thromboembolism in a large cohort recruited from the general population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-17)
Changes in the incidence of venous thromboembolism (VTE) during the last two decades have not been extensively studied. Therefore, we studied time trends in the incidence rates (IRs) of deep vein thrombosis (DVT) and pulmonary embolism (PE) in a cohort of 26,855 subjects, aged 25–97 years, enrolled in the Tromsø study in 1994/1995. The subject were followed-up throughout 2012, and all symptomatic, ...
Cystatin C is associated with risk of venous thromboembolism in subjects with normal kidney function - the Tromso study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
Background Previous studies have shown an association between impaired kidney function, assessed by cystatin C-based estimated glomerular filtration rate, and venous thromboembolism. The aim of this study was to investigate whether serum cystatin C was associated with a risk of venous thromboembolism among subjects with normal kidney function in a prospective population-based study.
Design and ...
Evaluation of the medical student research programme in Norwegian medical schools : a survey of students and supervisors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-14)
Background: The Medical Student Research Programme is a national education and grant scheme for medical
students who wish to carry out research in parallel with their studies. The purpose of the programme is to
increase recruitment of people with a standard medical degree to medical research. The Research Programme
was established in 2002 and underwent a thorough evaluation during the spring of ...
Red cell distribution width is associated with future risk of incident stroke. The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-20)
Red cell distribution width (RDW), a measure of the variability in size
of the circulating erythrocytes, is associated with cardiovascular morbidity
and mortality. We aimed to investigate whether RDW was associated
with incident stroke and case fatality in subjects recruited
from the general population. Baseline characteristics were obtained
from 25,992 subjects participating in the fourth ...
Atherosclerotic risk factors and risk of myocardial infarction and venous thromboembolism; Time-fixed versus time-varying analyses. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-16)
<i>Background:</i> Single measurements of modifiable risk factors may underestimate associations with outcomes in cohorts. We aimed to compare risk estimates of myocardial infarction (MI) and
venous thromboembolism (VTE) by atherosclerotic risk factors during long follow-up using
time-fixed analyses without and with correction for regression dilution and time-varying
analyses.<p>
<p><i>Methods:</i> ...
Weight Change and Risk of Venous Thromboembolism: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-20)
<b>Background:</b> Obesity is a major risk factor for venous thromboembolism (VTE), but it is unknown to what
extent weight change over time affects VTE risk.<br>
<b>Aims:</b> To investigate the association between weight change and risk of incident VTE in a population-based
cohort with repeated measurements.<br>
<b>Methods:</b>
Participant data were collected from the Tromsø 3 (1986–87), 4 ...
D-Dimer Measured At First Venous Thromboembolism Is Associated With Future Risk Of Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12)
D-dimer >5000 ng/ml at incident VTE is associated with a higher risk of subsequent cancer within one and two years. High D-dimer levels are also associated with more aggressive tumor biology and poor prognosis in these patients. As D-dimer is routinely measured in the assessment of suspected VTE, it may be a useful surrogate marker for the presence of an underlying malignancy. Our findings may suggest ...