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The Clinical Effectiveness of Web-Based Cognitive Behavioral Therapy With Face-to-Face Therapist Support for Depressed Primary Care Patients: Randomized Controlled Trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-08-05)
The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction and body height. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Objective: High serum thyrotropin (TSH) levels predict cardiovascular disease (CVD). Recently several single
nucleotide polymorphisms (SNPs) associated with TSH levels have been identified, one of them being the
rs4704397 SNP in the phosphodiesterase 8B (PDE8B) gene. If the relation between thyroid function and CVD is
causal, one could also expect rs4704397 genotypes to predict CVD and possibly ...
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects,
we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist
circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up
(additional 137,052 individuals) in a total ...
Evaluation of Serum 25-Hydroxyvitamin D as a Predictor of Carotid Intima-Media Thickness and Carotid Total Plaque Area in Nonsmokers: The Tromso Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Objective. Altered calcium homeostasis has been linked to increased intima-media thickness (IMT) and plaques. We aimed
to investigate whether serum 25-hydroxyvitamin D (25(OH)D) and serum calcium are associated with IMT and plaques in
nonsmoking population. Methods.Ultrasound of the right carotid arterywith themeasurements of IMT and plaqueswas performed
in 4194 nonsmoking subjects with available ...
Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether
body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM.
Methodology: S. aureus colonization ...
Factors associated with Chlamydia trachomatis testing in a high school based screening and previously in clinical practice: a cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
High school based chlamydia screening has been shown to increase uptake and detect hidden infections among sexually active adolescents. Our study aimed to: i) examine the proportions of 15–20 year-olds tested in a high school based screening and previously in clinical practice, ii) determine chlamydia prevalence according to testing pattern, and iii) examine factors associated with testing in the ...
Minimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus block
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-02-18)
<p><i>Background - </i>Ultrasound guidance has been shown to reduce the minimum effective volume (MEV) of local anaesthetics for several peripheral nerve blocks. Although the lateral sagittal infraclavicular block (LSIB) is a well‐established anaesthesia method, MEV for this technique has not been established. Our aim with this study was to determine the MEV using ropivacaine 7.5 mg/ml for the LSIB ...
Accuracy of physical examination for chronic lumbar radiculopathy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background: Clinical examination of patients with chronic lumbar radiculopathy aims to clarify whether there is
nerve root impingement. The aims of this study were to investigate the association between findings at clinical
examination and nerve root impingement, to evaluate the accuracy of clinical index tests in a specialised care
setting, and to see whether imaging clarifies the cause of chronic ...
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Genome-wide association studies (GWAS) have identified ~ 100 loci associated with blood lipid levels, but much of the trait
heritability remains unexplained, and at most loci the identities of the trait-influencing variants remain unknown. We
conducted a trans-ethnic fine-mapping study at 18, 22, and 18 GWAS loci on the Metabochip for their association with
triglycerides (TG), high-density ...