Avhandlingen presenterer behandlingseffekt, bivirkninger og livskvalitet hos lungekreftpasienter som får moderne cellegiftbehandling. Pasientene med performance status (PS) 2 er etterpå vurdert separat. <br><br>Avhandlingens tittel er ”Advanced non-small cell Lung Cancer – Effects of Chemotherapy and Impact on Health Related Quality of Life”. Den ble forsvart for graden PhD 13.03.2009. På verdensbasis ...

The present work includes women from three cohorts: the Norwegian Women and Cancer (NOWAC) study, the European Prospective Investigation into Cancer and Nutrition (EPIC) study, and a sub-cohort from the NOWAC study termed the Norwegian EPIC cohort (NEPIC). <br>Despite large differences in nutritional values in lean and fatty fish most studies on fish consumption and cancer do not diverse between ...

In July 1993, several measures to stimulate return to work, like Active Sick Listing, formal decisions on sick leave beyond 12 weeks and commitments for employers to consider potential job adjustment were incorporated. The role of sickness as main cause to be entitled sickness benefits was simultaneously emphasised. However, despite av increasing focus on improving the necessary medical certificates ...

Avhandlingens tema er utviklingen innenfor lokal samfunnsmedisinsk legetjeneste fra 1994 til 2002. Desentraliserings- og liberaliseringsreformer i primærhelsetjenesten, endringer i helseforhold og etterspørsel etter helsetjenester endret arbeidsarenaen for samfunnsmedisinerne, og gav økonomiske, organisatoriske og faglige utfordringer. Avhandlingen er basert på tre tverrsnittsundersøkelser, gjennom ...

Hjernesvulster utgjør en diagnostisk utfordring. Rask, sikker og skånsom prøvetagning er viktig for både pasient og lege da videre behandlingen er avhengig av type svulst og utbredelse av denne.Ved Nevrokirurgisk avdeling, Universitetssykehuset Nord-Norge er det utviklet en forenklet metode for prøvetagning av hjernesvulster. Vevsprøven kan tas i lokalbedøvelse og pasienten skrives ut av sykehuset ...

The Murmansk County Birth Registry (MCBR) was initiated on January 1. 2006. Currently (April 2009) the MCBR has registered over 26 000 births. The registry covers a geographical area known as the Kola Peninsula in Northwest Russia, which is almost entirely located above the Arctic Circle. Murmansk County is about half the size of Norway and had 857 000 inhabitants in 2008. All the 15 delivery ...

Liposomes play an important role in medical and pharmaceutical science as e.g. nanoscale drug carriers. One of their most important features is their size and size distribution, influencing both their biodistribution and passive targeting abilities upon intravenous administration. To this day there is no single method for size characterisation of liposomes that fulfils all following criteria: being ...

<b>Objective</b> <br>Placenta has an important function of sustaining life in utero. Role of placental gene expression in the physiology of parturition and pathogenesis of pregnancy disorders are poorly understood. The aims of this thesis were to: <br>1. Investigate the effect of labor on global gene expression profile of normal placentas <br>2. Compare placental gene expression profile of ...

Depression is a serious disorder due to its highly relapsing and recurrent course, thereby highlighting the necessity to identify vulnerability factors in order to prevent and treat its course. The present thesis investigated temperament and character traits, dysfunctional attitudes, and early maladaptive schemas (EMSs) in clinically depressed (CDs), previously depressed (PDs), and never depressed ...

Positron emission tomography is a non-invasive imaging modality allowing visualization and quantification of a wide variety of physiological and biochemical processes or of a specific lowdensity protein target. Some examples are blood flow, glucose consumption, fatty acid metabolism or detection and quantification of cell surface receptors in particular tissues. Within the spectrum of available ...