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Estrogen receptor alpha gene polymorphism and endometrial cancer risk : a case-control study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-11-06)
Background: Estrogen is an established endometrial carcinogen. One of the most important mediators of estrogenic action is the estrogen receptor alpha. We have investigated whether polymorphic variation in the estrogen receptor alpha gene (ESR1) is associated with endometrial cancer risk. <br> Methods: In 702 cases with invasive endometrial cancer and 1563 controls, we genotyped five markers ...