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Atrial fibrillation is associated with cognitive decline in stroke-free subjects: the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-28)
Background and purpose:<br>Previous studies have shown associations between atrial fibrillation (AF) and cognitive decline. We investigated this association in a prospective population study, focusing on whether stroke risk factors modulated this association in stroke-free women and men.<br>Methods:<br>We included 4983 participants (57% women) from the fifth survey of the Tromsø Study (Tromsø 5, ...
Sex Differences in the Impact of Body Mass Index on the Risk of Future Atrial Fibrillation: Insights From the Longitudinal Population-Based Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-19)
<p><i>Background</i>: Atrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated.</p>
<p><i>Methods and Results</i>: Data from the fourth survey (1994–1995) of the Tromsø Study (Norway) were used to investigate the association of single‐measurement BMI on future AF ...
Polymorphisms Related to the Serum 25-Hydroxyvitamin D Level and Risk of Myocardial Infarction, Diabetes, Cancer and Mortality. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
Low serum 25(OH)D levels are associated with cardiovascular risk factors, and also predict future myocardial infarction (MI), type 2 diabetes (T2DM), cancer and all-cause mortality. Recently several single nucleotide polymorphisms (SNPs) associated with serum 25-hydroxyvitamin D (25(OH)D) level have been identified. If these relations are causal one would expect a similar association between these ...
Association of occasional smoking with total mortality in the population-based Tromsø study, 2001-2015
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-28)
Objectives: <br> There is a shift in the smoking population
from daily smokers to light or occasional smokers. The
knowledge about possible adverse health effects of this
new smoking pattern is limited. We investigated smoking
habits with focus on occasional smoking in relation to
total mortality in a follow-up study of a Norwegian general
population. <br>
Setting: <br> A population study ...
CHA2DS2-VASc score, left atrial size and atrial fibrillation as stroke risk factors in the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-01)
Objective:<br> CHA2DS2-VASc score, left atrial (LA) size and atrial fibrillation (AF) have individually been associated with stroke risk. Our aim was to investigate the predictive ability of combinations of these factors for the odds of incident stroke in a population-based cohort study.<br>
Methods:<br> We followed 2844 participants from the Tromsø Study from 1994 to 2012. Information on LA size ...
Genetic variations in the Vitamin D receptor predict type 2 diabetes and myocardial infarction in a community-based population: The tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-23)
Background
Though the associations between low serum 25-hydroxyvitamin D (25(OH)D) levels and
health outcomes such as type 2 diabetes (T2D), myocardial infarction (MI), cancer, and
mortality are well-studied, the effect of supplementation with vitamin D is uncertain. This
may be related to genetic differences. Thus, rs7968585, a single nucleotide polymorphism
(SNP) of the vitamin D receptor ...
Association between diastolic dysfunction and future atrial fibrillation in the Tromsø Study from 1994 to 2010
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-13)
Objective. To investigate the association between echocardiographic measurements with emphasis on diastolic dysfunction and risk of atrial fibrillation (AF) in a population-based cohort study.
Methods. We followed 2406 participants from the Tromsø Study from 1994 to 2010. Left atrial (LA) size and mitral Doppler indices as measured by echocardiography were used for evaluating diastolic dysfunction. ...
Incidence of and risk factors for type-2 diabetes in a general population: The Tromso Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
Risk factors for type 2 diabetes in groups stratified according to metabolic syndrome : a 10-year follow-up of The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
Many incident cases of type 2 diabetes do not
fulfill the metabolic syndrome, which accordingly has been questioned both as a research and clinical tool. The aim of this study was to determine differences in risk factors for type 2 diabetes between groups with high or low metabolic
score. The study population were 26,093 men and women attending the Tromsø Study in 1994, followed through 2005, and ...
The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction and body height. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Objective: High serum thyrotropin (TSH) levels predict cardiovascular disease (CVD). Recently several single
nucleotide polymorphisms (SNPs) associated with TSH levels have been identified, one of them being the
rs4704397 SNP in the phosphodiesterase 8B (PDE8B) gene. If the relation between thyroid function and CVD is
causal, one could also expect rs4704397 genotypes to predict CVD and possibly ...