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The DBP Phenotype Gc-1f/Gc-1f is associated with reduced risk of cancer. The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-18)
Background and Objective In addition to its role as a transport protein, the vitamin D binding protein (DBP) may also affect lipid metabolism, inflammation and carcinogenesis. There are three common variants of the DBP, Gc1s (1s), Gc1f (1f), Gc2 (2) that result in six common phenotypes (1s/1s, 1s/ 1f, 1s/2, 1f/1f, 1f/2, and 2/2). These phenotypes can be identified by genotyping for the two single ...