Now showing items 1-2 of 2
No lipid lowering effect of vitamin D supplements found on statin users.
(Master thesis; Mastergradsoppgave, 2015-08-26)
Background Tromsø endocrine research group has performed multiple RCTs with vitamin D supplements/placebo and effects on different outcomes. Compiling data from four of these studies I tested an hypothesis established by Kane et al. in 2013, which suggests that vitamin D supplements have a significant lipid lowering effect in statin users. Retesting hypotheses in general is vital to the scientific ...
Serum free and bio-available 25-hydroxyvitamin D correlate better with bone density than serum total 25-hydroxyvitamin D
(Master thesis; Mastergradsoppgave, 2015-10-29)
Introduction/background In the circulation 25-hydroxyvitamin D (25(OH)D) is bound to vitamin D-binding protein (DBP) and albumin. Only a small fraction is in the unbound, free form. According to the ‘free-hormone-hypothesis’ only the free form is biologically active. Genetic differences in DBP may affect the binding to 25(OH)D and thereby the amount of free 25(OH)D. Methods In the present study ...