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The butterfly design as an alternative to the "double-A" bilateral flaps for the treatment of sacral defects
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-04)
Letter to the Editor
Endringer i forskningsaktiviteten ved Universitetssykehuset Nord-Norge 2000 - 2005
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006)
Bakgrunn: Norsk medisinsk forskning hevder seg dårlig i nordisk sammenheng. Ved UniversitetssykehusetNord-Norge (UNN) ble forskningsaktivitet og hindringer for klinisk forskning undersøktmed en spørreskjemaundersøkelse i år 2000. Denne undersøkelsen er nå gjentatt etter fem år for å se omforholdene er endret.Materiale og metode: Alle leger og psykologer ved UNN fikk i mai 2005 tilsendt det samme ...
Site-specific reverse splicing of a HEG-containing group I intron in ribosomal RNA
(Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
The myxomycete Didymium iridis (isolate Panama 2)
contains a mobile group I intron named Dir.S956-1
after position 956 in the nuclear small subunit (SSU)
rRNA gene. The intron is efficiently spread through
homing by the intron-encoded homing endonuclease
I-DirI. Homing endonuclease genes (HEGs) usually
spread with their associated introns as a unit, but
infrequently also spread independent ...
Complete mitochondrial genome sequences of the Arctic Ocean codfishes Arctogadus glacialis and Boreogadus saida reveal oriL and tRNA gene duplications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-05-27)
We have determined the complete mitochondrial
genome sequences of the codWshes Arctogadus glacialis
and Boreogadus saida (Order Gadiformes, Family
Gadidae). The 16,644 bp and 16,745 bp mtDNAs, respectively,
contain the same set of 37 structural genes found in
all vertebrates analyzed so far. The gene organization is
conserved compared to other Gadidae species, but with one
notable exception. ...
Plasma levels of leptin and mammographic density among postmenopausal women. A cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-09-29)
Introduction Obesity has been linked to increased risk of breast
cancer in postmenopausal women. Increased peripheral
production of estrogens has been regarded as the main cause
for this association, but other features of increased body fat
mass may also play a part. Leptin is a protein produced mainly
by adipose tissue and may represent a growth factor in cancer.
We examined the association ...
Reliability of sickness certificates in detecting potential sick leave reduction by modifying working conditions. A clinical epidemiology study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2004-03-25)
Background:
Medical sickness certificates are generally the main source for information when scrutinizing the need for aimed intervention strategies to avoid or reduce the individual and community side effects of sick leave. This study explored the value of medical sickness certificates related to daily work in Norwegian National Insurance Offices to identify sick-listed persons, where modified ...
Different measures of smoking exposure and mammographic density in postmenopausal Norwegian women : a cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2007-10-26)
Background: Recent cohort studies have suggested an
increased risk of breast cancer with long duration of smoking,
and with smoking initiation before first birth. Cigarette smoking
may have both carcinogenic effects and antiestrogenic effects
on the breast tissue. We decided to examine the relationship
between different measures of smoking exposure and
mammographic density.
Methods: Lifetime ...
Use of hormonal contraceptives and occurrence of pregnancy-related pelvic pain. A prospective cohort study in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2004-06-22)
Background:
Pregnancy-related pelvic pain is a common condition, and use of hormonal contraceptives before pregnancy has been proposed as a risk factor. We used data from a sub-sample of women participating in the "Norwegian Women and Cancer study" (NOWAC) to assess the association between hormonal contraceptive use and pelvic pain in pregnancy.
Methods:
From a sub-group of 2078 parous women ...
A third approach to gene prediction suggests thousands of additional human transcribed regions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-03)
The identification and characterization of the complete ensemble of genes is a main goal of deciphering the digital
information stored in the human genome. Many algorithms for computational gene prediction have been described,
ultimately derived from two basic concepts: (1) modeling gene structure and (2) recognizing sequence similarity.
Successful hybrid methods combining these two concepts have ...
Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2007-09-06)
Background:
Multidrug resistance is a particular limitation to cancer chemotherapy, antibiotic treatment and HIV medication. The ABC (ATP binding cassette) transporters human P-glycoprotein (ABCB1) and the human MRP5 (ABCC5) are involved in multidrug resistance.
Results:
In order to elucidate structural and molecular concepts of multidrug resistance, we have constructed a molecular model of the ...