Now showing items 1-10 of 414
A randomised clinical trial on the impact of early intervention on parental child-rearing attitudes and cognitive, motor and behavioral outcomes in preterm infants.
(Doctoral thesis; Doktorgradsavhandling, 2011-09-23)
BACKGROUND: Preterm infants are at increased risk of cognitive problems/delay and behavioual problems in the long term. Studies have shown that their mothers are more overprotective, and find it hard to implement a nurturant child rearing practice compared to parents of term infants. To improve the parent-infant interaction and thereby influence infant development in a beneficial different early ...
Cardioprotection : focus on Gap Junctions, Hemichannels and Mitochondria
(Doctoral thesis; Doktorgradsavhandling, 2012-05-04)
I studiene har vi undersøkt hjerteceller og isolerte hjerter under forhold som ligner på hjerteinfarkt. Denne kunnskapen brukte vi videre til å redusere hjerteinfarkt på rottehjerter. Vi har sett på effekten av hjerteinfarkt på mitokondrier og spesielle kanaler i hjertet som heter gap junctions og halvkanaler. Vi har vist at ved å holde spesielle halvkanaler lukket noen få minutter etter ett ...
The ACUFLASH study. Acupuncture treatment for postmenopausal hot flashes : can traditional Chinese acupuncture in addition to self-care reduce hot flash frequency and intensity, compared with self-care alone?
(Doctoral thesis; Doktorgradsavhandling, 2010-04-16)
Introduction. Hot flashes and night sweats are the most prevalent symptoms in menopause. Hormone therapy with oestrogen is considered the most effective treatment. However, recent research show that long term use of oestrogen increases the risk of serious adverse effects, and women and their health care providers are looking for alternatives. Acupuncture is one of the most frequently used complementary ...
Molecular diagnosis of low intensity Schistosoma japonicum infections
(Doctoral thesis; Doktorgradsavhandling, 2010-03-08)
<i>Introduction:</i> <br>Schistosoma japonicum is a parasitic fluke. The adult worms live as a pair in the small mesenteric blood vessels along the intestines. The eggs are excreted in the stool. It is endemic mainly in parts of China and the Philippines with the estimated prevalence in humans exceeding a million cases. Successful control programmes have run for several decades with the result that ...
Sonosensitive liposomes for ultrasound-mediated drug delivery
(Doctoral thesis; Doktorgradsavhandling, 2011-06-20)
Liposome encapsulation of cytotoxic drugs favours drug delivery to tumours and improves the therapeutic-to-toxicity ratio of conventional chemotherapy. A novel approach to further enhance the availability of liposomal drugs to tumour cells is to combine ultrasound (US) with US sensitive (sonosensitive) liposomes. US treatment of tumour tissue induces local drug release from the liposome carrier ...
Clinical and genetic investigations of patients with myotonia congenita in Northern Norway
(Doctoral thesis; Doktorgradsavhandling, 2012-02-10)
Femten norske og tre svenske familier med klinisk diagnostisert ’kongenitt myotoni (MC)’ er inkludert i studiet. Alle pasienter likesom deres førstegrads slektninger er undersøkt nøye klinisk og elektromyografisk (EMG). Systematisk undersøkelse av CLCN1 gen er da utført for å finne mutasjoner. Nye mutasjoner blir studert med uttrykks studie for å finne ut deres funksjonelle konsekvens på kanal ...
The clinical pharmacist's role in post-discharge follow-up of patients with coronary heart disease. A follow-up program.
(Doctoral thesis; Doktorgradsavhandling, 2012-04-13)
Coronary heart disease (CHD) is the leading cause of death world-wide. Studies indicate that patients are treated inadequately. Pharmaceutical care programs delivered by pharmacists are known to improve quality of care for patients with a variety of chronic and acute diseases, also CHD. Most of the programs are developed and carried out in the United States and United Kingdom. The overall aim of ...
Psychosocial predictors of an interest in cosmetic surgery : based on a population study of young Norwegian women
(Doctoral thesis; Doktorgradsavhandling, 2012-03-30)
This thesis aims to provide more knowledge about psychological and social aspects of cosmetic surgery, in particular what factors are associated with the increased interest in having such surgery oneself. The first paper is angled from a more public health perspective, with focus on what factors predicts whether someone considers having cosmetic surgery in general. In the second paper, the focus ...
LDL apheresis beyond lipid reduction : a study of three different apheresis columns in heterozygous familial hypercholesterolemia and ex vivo
(Doctoral thesis; Doktorgradsavhandling, 2012-06-01)
When low density lipoprotein (LDL) cholesterol cannot be adequately controlled by medications, it is possible to reduce LDL-cholesterol by means of LDL apheresis. This extracorporeal treatment is most often used in familial hypercholesterolemia (FH). The procedure is known to reduce LDL-cholesterol significantly. Few studies however, have prospectively and systematically examined how different LDL ...
Epidemiology and Outcome of Ankylosing Spondylitis in Northern Norway
(Doctoral thesis; Doktorgradsavhandling, 2012-05-29)