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A comprehensive analysis of the androgen receptor gene and risk of breast cancer. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-09-20)
Introduction Androgens have been hypothesised to influence risk of breast cancer through several possible mechanisms, including their conversion to estradiol or their binding to the oestrogen receptor and/or androgen receptor (AR) in the breast. Here, we report on the results of a large and comprehensive study of the association between genetic variation in the AR gene and risk of breast cancer ...
Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-13)
Introduction: The introduction of high-throughput technologies, also called -omics technologies, into epidemiology has raised the need for high-quality observational studies to reduce several sources of error and bias. Methods: The Norwegian Women and Cancer (NOWAC) postgenome cohort study consists of approximately 50,000 women born between 1943 and 1957 who gave blood samples between 2003 ...
Socioeconomic differences in cancer survival : the Norwegian Women and Cancer Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-06-08)
Background: Cancer survival has been observed to be poorer in low socioeconomic groups, but the knowledge about the underlying causal factors is limited. The purpose of this study was to examine how cancer survival varies by socioeconomic status (SES) among women in Norway, and to identify factors that explain this variation. SES was measured by years of education and gross household income, ...
Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-29)
Background: Gonadotropin releasing hormone (GNRH1) triggers the release of follicle stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene encoding GNRH1 or its receptor may influence breast cancer risk by modulating production of ovarian steroid hormones. We studied the association between breast cancer risk and polymorphisms in genes that code for GNRH1 ...
Test-retest reproducibility of a food frequency questionnaire (FFQ) and estimated effects on disease risk in the Norwegian Women and Cancer Study (NOWAC)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-01-31)
Background: The Norwegian Women and Cancer Study (NOWAC) is a national population-based cohort study with 102 443 women enrolled at age 30–70 y from 1991 to 1997. The present study was a methodological sub-study to assess the test-retest reproducibility of the NOWAC food frequency questionnaire (FFQ), and to study how measurement errors in the data can affect estimates of disease risk. Methods: A ...
Use of hormonal contraceptives and occurrence of pregnancy-related pelvic pain. A prospective cohort study in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2004-06-22)
Background: Pregnancy-related pelvic pain is a common condition, and use of hormonal contraceptives before pregnancy has been proposed as a risk factor. We used data from a sub-sample of women participating in the "Norwegian Women and Cancer study" (NOWAC) to assess the association between hormonal contraceptive use and pelvic pain in pregnancy. Methods: From a sub-group of 2078 parous women ...
Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries : a prospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2007-02-15)
Background: Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution. Methods: We have estimated exposure to Environmental Tobacco Smoke (ETS) and to air pollution in never smokers and ex-smokers ...
A comprehensive assessment of fish and other seafood in the Norwegian diet
(Research report; Forskningsrapport, 2006-03-27)
At the request of the Norwegian Food Safety Authority, the Norwegian Scientific Committee for Food Safety (VKM) has conducted an assessment of the nutritional benefits of consuming fish and other seafood, compared with the health risks associated with the intake of contaminants and other undesirable compounds that fish and other seafood may contain.
Cancer incidence in Arkhangelskaja Oblast in northwestern Russia. The Arkhangelsk Cancer Registry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2005-07-19)
Background: Data concerning incidence and prevalence of cancer in the different regions of Russia have traditionally not been provided on a basis that facilitated comparison with data from countries in western parts of Europe. The oncological hospital in Arkhangelsk, in co-operation with Universitetet i Tromsø (Norway), has established a population based cancer registry for Arkhangelskaja Oblast ...
Percentage density, Wolfe's and Tabár's mammographic patterns. Agreement and association with risk factors for breast cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2005-08-25)
Introduction: The purpose of this report was to classify mammograms according to four methods and to examine their agreement and their relationship to selected risk factors for breast cancer. Method: Mammograms and epidemiological data were collected from 987 women, aged 55 to 71 years, attending the Norwegian Breast Cancer Screening Program. Two readers each classified the mammograms according ...