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Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
Insulin‐like growth factor‐I (IGF‐I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF‐I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF‐I concentrations ...
Lifetime alcohol use and overall and cause-specific mortality in the European Prospective Investigation into Cancer and nutrition (EPIC) study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Combined impact of healthy lifestyle factors on colorectal cancer: A large European cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-05)
The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.
Methods The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs. ...
Consumption of dairy products and colorectal cancer in the European prospective investigation into cancer and nutrition (EPIC)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of
total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for
individual dairy products with differing fat contents.
Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), ...
Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids
[SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically,
the relevance of food sources of SFAs to CHD associations is uncertain.<p>
METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...
Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-07)
Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne ...
Dietary advanced glycation end-products and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective
cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of
dAGEs in the European Prospective ...
Ovarian cancer risk factors by tumor aggressiveness: An analysis from the Ovarian Cancer Cohort Consortium
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-18)