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Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-07)
Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne ...
Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort
(Journal article; Peer reviewed, 2018-05-22)
Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at ...
Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-18)
<p><i>Background</i>: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential ...
Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-23)
<i>Background</i> - The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex diseases.<p>
<p><i>Objectives</i> - First, to summarize the main design features of a prospective case-control study –nested within the European Prospective Investigation ...
Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...
Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
Background: Results from several cohort and case–control studies suggest a protective association between current alcohol
intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain
unanswered.<p>
<p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid
carcinoma ...
Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: A multinational cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
<i>Background & Aims</i>
- Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision.<p><p>
<i>Methods</i>
- In the European Prospective Investigation ...
Plasma polyphenols associated with lower high-sensitivity C-reactive protein concentrations: A cross-sectional study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-04)
Experimental studies have reported on the anti-inflammatory properties of polyphenols. However, results from epidemiological investigations have been inconsistent and especially studies using biomarkers for assessment of polyphenol intake have been scant. We aimed to characterise the association between plasma concentrations of thirty-five polyphenol compounds and low-grade systemic inflammation ...
Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the Pan-European EPIC Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
<i>Background</i>
- There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition).<P><P>
<i>Methods</i>
- In this prospective study of 409 885 men and women in 9 European countries, diet ...
Association between soft drink consumption and mortality in 10 European countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
<i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p>
<i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p>
<i>Design, ...