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Effective filtering strategies to improve data quality from population-based whole exome sequencing studies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Family History of Myocardial Infarction and Cause-Specific Risk of Myocardial Infarction and Venous Thromboembolism - The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
The increased risk of venous thromboembolism by advancing age cannot be attributed to the higher incidence of cancer in the elderly: the Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Atrial fibrillation and future risk of venous thromboembolism:the Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Existing data sources in clinical epidemiology: The Scandinavian Thrombosis and Cancer Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-16)
Background: Although venous thromboembolism (VTE) is a known common complication in
cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in
the general population. The Scandinavian Thrombosis and Cancer (STAC) Cohort was established
by merging individual data from three large Scandinavian cohorts (The Tromsø Study, the second
Nord-Trøndelag Health Study, ...
Thyroid function, as assessed by TSH, and future risk of venous thromboembolism: The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-21)
Objective: The relationship between thyroid function and the risk of venous thromboembolism (VTE) has not been addressed in population-based cohorts. We investigated the association between TSH levels and the risk of VTE in a general adult population.
Design: Population-based cohort study.
Methods: TSH was measured in 11 962 subjects aged 25–89 years who participated in Tromsø 4–6 starting in ...
Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
The low density lipoprotein receptor-related protein-1 (LRP-1) is a large, multifunctional endocytic receptor from the LDL receptor family, highly expressed in liver parenchymal cells (PCs), neurons, activated astrocytes, and fibroblasts. The aim of the study was to investigate if liver sinusoidal endothelial cells (LSECs), highly specialized scavenger cells, express LRP-1. To address this question, ...
The apolipoprotein C-I content of very-low-density lipoproteins is associated with fasting triglycerides, postprandial lipemia, and carotid atherosclerosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Experimental studies in animals suggest that apolipoprotein (apo) C-I is an important regulator of triglycerides in fasting and postprandial conditions and associated with carotid atherosclerosis. Methods. A cross-sectional study was conducted with 81 subjects, aged 56–80 years recruited from a population health survey. The participants underwent a fat tolerance test (1 g fat per Kg body weight) and ...
Serum osteoprotegerin levels are related to height loss : the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Severe loss of body height is often a consequence of osteoporotic vertebral fractures. Osteoprotegerin (OPG) and receptor activator of nuclear factor-kB ligand (RANKL) are cytokines essential for the regulation of bone resorption. The aim of this study was to assess the relationship between the OPG/RANKL system and height loss. A total of 4,435 inhabitants from the municipality of Tromsø, ...
Impact of incident venous thromboembolism on risk of arterial thrombotic diseases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11-22)
BACKGROUND: Growing evidence supports an association between venous thromboembolism (VTE) and arterial thrombotic diseases (ie, myocardial infarction and ischemic stroke). We aimed to study the association between VTE and future arterial events and to determine the population attributable risk of arterial events by VTE in a large prospective cohort recruited from the general population. METHODS AND ...