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Macular thickness in healthy eyes of adults (N=4508) and relation to sex, age and refraction: The Tromsø Eye Study (2007-08)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-18)
Purpose: To provide sex-stratified normative data on retinal thickness and study
the relationship with sex, age and refractive status.
Methods: Population-based study including 2617 women and 1891 men, aged 38–
87 (mean 61 8) years, without diabetes, glaucoma and retinal diseases, and
spherical equivalent refraction (SER) within 6 dioptres. Retinal thickness was
measured with optical coherence ...
Associations between Common and Rare Exonic Genetic Variants and Serum Levels of 20 Cardiovascular-Related Proteins: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-21)
Background—Genetic variation can be used to study causal relationships between biomarkers and diseases. Here, we
identify new common and rare genetic variants associated with cardiovascular-related protein levels (protein quantitative
trait loci [pQTLs]). We functionally annotate these pQTLs, predict and experimentally confirm a novel molecular
interaction, and determine which pQTLs are associated ...
Single versus multiple-family intervention in childhood overweight - Finnmark Activity School: A randomised trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
High prevalence of overweight and obesity among 6-year-old children in Finnmark County, North Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
Blood pressure target achievement and antihypertensive medication use in women and men after first-ever myocardial infarction: the Tromsø Study 1994-2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-03)
Background: <br>
Recurrent cardiovascular events after
myocardial infarction (MI) are frequent,
and gender
differences in blood pressure treatment have been
reported. Despite increased focus on secondary
prevention, recent reports indicate that treatment targets
are not achieved. There is a need for gender-specific
analyses of post-MI blood pressure treatment target
achievement and ...
Serum osteoprotegerin and renal function in the general population: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-03)
<p><i>Background</i>:
Serum osteoprotegerin (OPG) is elevated in patients with chronic kidney disease (CKD) and increases with decreasing renal function. However, there are limited data regarding the association between OPG and renal function in the general population. The aim of the present study was to explore the relation between serum OPG and renal function in subjects recruited from the general ...
Impact of Chronic Inflammation, Assessed by hs-CRP, on the Association between Red Cell Distribution Width and Arterial Cardiovascular Disease: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-10)
Red cell distribution width (RDW), a measure of variability in size of circulating
erythrocytes, is associated with arterial cardiovascular disease (CVD), but the
underlying mechanism remains unclear. We aimed to investigate the impact of
chronic inflammation as measured by high sensitivity CRP (hs-CRP) on this
relationship, and explore whether RDW could be a mediator in the causal pathway
between ...
High-sensitivity C-reactive protein is not a risk factor for venous thromboembolism: the Tromso study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
High-sensitivity C-reactive protein is associated with risk of arterial cardiovascular disease but
conflicting results have been reported on its role in venous thromboembolic disease. The objective of our study was to investigate the association between high-sensitivity C-reactive protein levels and risk of future venous thromboembolism in a prospective cohort recruited from a general population. ...
Family History of Myocardial Infarction and Cause-Specific Risk of Myocardial Infarction and Venous Thromboembolism - The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
Estimated and Measured GFR Associate Differently with Retinal Vasculopathy in the General Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11)
Background/Aims: Estimated GFR (eGFR) is used extensively in epidemiological research.
Validations of eGFR have demonstrated acceptable performance, but the dependence of
creatinine and cystatin C on non-GFR factors could confound associations with disease. Few
studies have investigated this issue in direct comparison with measured GFR (mGFR). We
compared the associations between eGFR and mGFR ...