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Decentralization matters : differently organized mental health services relationship to staff competence and treatment practice : the VELO study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
EMMA 2-A MAGE-compliant system for the collaborative analysis and integration of microarray data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
Intensity Dependent Confidence Intervals on Microarray Measurements of Differentially Expressed Genes : A Case Study of the Effect of MK5, FKRP and TAF4 on the Transcriptome
(Journal article; Tidsskriftartikkel; Peer reviewed, 2007)
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-05-02)
Background
Ribosomal DNA of several species of the free-living Naegleria amoeba harbors an optional group I intron within the nuclear small subunit ribosomal RNA gene. The intron (Nae.S516) has a complex organization of two ribozyme domains (NaGIR1 and NaGIR2) and a homing endonuclease gene (NaHEG). NaGIR2 is responsible for intron excision, exon ligation, and full-length intron RNA circularization, ...
Delayed leukocytosis after hard strength and endurance exercise. Aspects of regulatory mechanisms
(Journal article; Tidsskriftartikkel; Peer reviewed, 2003-12-11)
Background:
During infections, polymorphonuclear neutrophilic granulocytes (PMN) are mobilized from their bone marrow stores, travel with blood to the affected tissue, and kill invading microbes there. The signal(s) from the inflammatory site to the marrow are unknown, even though a number of humoral factors that can mobilize PMN, are well known. We have employed a standardized, non-infectious ...
Scavenger properties of cultivated pig liver endothelial cells
(Journal article; Tidsskriftartikkel; Peer reviewed, 2004-08-12)
Background:
The liver sinusoidal endothelial cells (LSEC) and Kupffer cells constitute the most powerful scavenger system in the body. Various waste macromolecules, continuously released from tissues in large quantities as a consequence of normal catabolic processes are cleared by the LSEC. In spite of the fact that pig livers are used in a wide range of experimental settings, the scavenger ...
Extravascular lung water assessed by transpulmonary single thermodilution and postmortem gravimetry in sheep
(Journal article; Tidsskriftartikkel; Peer reviewed, 2004-10-19)
Introduction:
Acute lung injury is associated with accumulation of extravascular lung water (EVLW). The aim of the present study was to compare two methods for quantification of EVLW: transpulmonary single thermodilution (EVLWST) and postmortem gravimetric (EVLWG).
Methods:
Eighteen instrumented and awake sheep were randomly assigned to one of three groups. All groups received Ringer's ...
Characterisation of parapoxviruses isolated from Norwegian semi-domesticated reindeer (Rangifer tarandus tarandus)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2005-09-05)
Background: Two outbreaks of the disease contagious ecthyma were reported in 1999 and 2000
in Norwegian semi-domesticated reindeer (Rangifer tarandus tarandus). Contagious ecthyma is an
epidermal disease of sheep and goats worldwide, which is caused by the zoonotic parapoxvirus orf
virus. Characterisation of clinical samples from the two outbreaks in semi-domesticated reindeer
in Norway by ...
Liver sinusoidal endothelial cells represents an important blood clearance system in pigs
(Journal article; Tidsskriftartikkel; Peer reviewed, 2003-01-03)
Background:
Numerous studies in rats and a few other mammalian species, including man, have shown that the sinusoidal cells constitute an important part of liver function. In the pig, however, which is frequently used in studies on liver transplantation and liver failure models, our knowledge about the function of hepatic sinusoidal cells is scarce. We have explored the scavenger function of pig ...
Circular instead of hierarchical. Methodological principles for the evaluation of complex interventions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2006-06-24)
Background: The reasoning behind evaluating medical interventions is that a hierarchy of
methods exists which successively produce improved and therefore more rigorous evidence based
medicine upon which to make clinical decisions. At the foundation of this hierarchy are case studies,
retrospective and prospective case series, followed by cohort studies with historical and
concomitant non-randomized ...