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General Practitioners’ Decisions to Refer Patients to Secondary Care – Referral Rates, Reasons for Referral and Expected Medical Benefit of the Referrals
(Doctoral thesis; Doktorgradsavhandling, 2015-04-09)
Summary Background The referral rates of general practitioners (GPs) are an important determinant of secondary care utilisation. The considerable variation in these rates between GPs cannot be explained by patient morbidity alone. Other factors, like health care organisation, GP characteristics and patient preference play an important role, but the extent of their mutual contributions is not ...
Extended-spectrum β-lactamases and carbapenemases in clinical isolates of Enterobacteriaceae in Norway. Aspects of detection and epidemiology.
(Doctoral thesis; Doktorgradsavhandling, 2015-04-16)
The Epidemiology of Valvular Aortic Stenosis. Prevalence, incidence, mortality, risk factors and progression of aortic stenosis in a general population. The Tromsø Study.
(Doctoral thesis; Doktorgradsavhandling, 2015-11-19)
With datasets from 3 repeated echocardiographic examinations (1994, 2001 and 2008) of a random sample of initially 3,273 participants in the Tromsø Study, we were able to give descriptive and analytical epidemiologic data on degenerative aortic valve disease. Aortic valve stenosis (AS) was defined as a mean aortic valve gradient ≥15 mmHg. There were 164 subjects with AS. We found that prevalence ...
Identification of novel roles and new modes of regulation for the atypical MAP kinases ERK3 and ERK4
(Doctoral thesis; Doktorgradsavhandling, 2015-11-13)
The atypical MAP kinases ERK3 and ERK4 are the main characters in this study. ERK3 and ERK4 were for long considered as orphan proteins without known upstream activators. However, in 2011 two studies had detected that group I p-21 protein activated kinase (PAKs) can constitutively phosphorylate ERK3 and ERK4 in their activation loop. The only well-characterized substrate for ERK3 and ERK4 at that ...
Immune properties of cry1Ab transgenic maize studied in mouse models of airway and food allergy
(Doctoral thesis; Doktorgradsavhandling, 2015-03-19)
The genetically modified maize event MON810 has been inserted with a processed version of the transgene, cry1ab, derived from the soil bacterium Bacillus thuringiensis (Bt) to express proteins with insecticidal properties. The introduced toxin may confer risks of immunogenicity, allergenicity and/or adjuvanticity to humans as well as domestic and wild animals, via inhalation of pollen and plant ...
Antibiotic use Human consumption patterns and effect on bacteria
(Doctoral thesis; Doktorgradsavhandling, 2015-03-17)
Prescriptions of antibiotics in Norway, and the effect of antibiotics on bacteria were investigated. The aim was to describe the consumption of antibiotics through prescriptions to patients and address how antibiotics can favour bacterial resistance. Several methods were applied, multivariate statistics, quantile regression and mathematical modelling of experimental conditions aided in the investigations. ...
The Clinician in Leadership. Perceptions of Style. Perspectives from Rural Primary Medicine in Norway.
(Doctoral thesis; Doktorgradsavhandling, 2014-08-22)
Health education and self care in dentistry : surveys and interventions.
(Doctoral thesis; Doktorgradsavhandling, 1989)
Aspects of breast cervical cancer screening
(Doctoral thesis; Doktorgradsavhandling, 1992)
The purpose of the thesis was to investigate aspects of breast cancer screening such as the feasibility, non-attendance and adverse effects of a general mammography screening program. A second objective was to examine whether risk factors for cervical neoplasia could be identified for potential utilization in a selective screening program for cervical cancer.
Fractional exhaled nitric oxide and its relation to exercise, asthma and allergic rhinoconjunctivitis in a subarctic childhood population. A study of asthma and allergy among schoolchildren in Nordland County.
(Doctoral thesis; Doktorgradsavhandling, 2014-11-07)
Astma og allergisk øye- og nesekatarr (rhinokonjunktivitt, AR) er de vanligste kroniske sykdommene blant barn i den vestlige verden. I de siste tiårene har prevalensen (forekomsten) av sykdommene økt betydelig, men i enkelte Europeiske land rapporteres det om en utflating i prevalensen av astma. I klinisk praksis brukes laboratorietester til å understøtte diagnosene astma og AR. Analyser av biologiske ...