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Evaluation of Serum 25-Hydroxyvitamin D as a Predictor of Carotid Intima-Media Thickness and Carotid Total Plaque Area in Nonsmokers: The Tromso Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Objective. Altered calcium homeostasis has been linked to increased intima-media thickness (IMT) and plaques. We aimed
to investigate whether serum 25-hydroxyvitamin D (25(OH)D) and serum calcium are associated with IMT and plaques in
nonsmoking population. Methods.Ultrasound of the right carotid arterywith themeasurements of IMT and plaqueswas performed
in 4194 nonsmoking subjects with available ...
Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether
body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM.
Methodology: S. aureus colonization ...
Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)
Factors associated with Chlamydia trachomatis testing in a high school based screening and previously in clinical practice: a cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
High school based chlamydia screening has been shown to increase uptake and detect hidden infections among sexually active adolescents. Our study aimed to: i) examine the proportions of 15–20 year-olds tested in a high school based screening and previously in clinical practice, ii) determine chlamydia prevalence according to testing pattern, and iii) examine factors associated with testing in the ...
Minimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus block
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-02-18)
<p><i>Background - </i>Ultrasound guidance has been shown to reduce the minimum effective volume (MEV) of local anaesthetics for several peripheral nerve blocks. Although the lateral sagittal infraclavicular block (LSIB) is a well‐established anaesthesia method, MEV for this technique has not been established. Our aim with this study was to determine the MEV using ropivacaine 7.5 mg/ml for the LSIB ...
Effect of genetically low 25-hydroxyvitamin D on mortality risk: Mendelian randomization analysis in 3 large European cohorts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-02)
The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship by using a Mendelian randomisation (MR) approach with genetic variants in the vitamin D synthesis pathway. Individual participant data from three European cohorts were harmonized with standardization of 25(OH)D according to the Vitamin D ...
Mild Albuminuria Is a Risk Factor for Faster GFR Decline in the Nondiabetic Population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-08)
<i>Introduction</i>: A minimal increase in the albumin-to-creatinine ratio (ACR) predicts cardiovascular disease
and mortality, but whether it predicts kidney function loss in nondiabetic persons is unclear. We investigated the association between ACR in the optimal or high-normal range and the rate of glomerular
filtration rate (GFR) decline in a cohort from the general population without diabetes, ...
A novel combination of peripheral nerve blocks for arthroscopic shoulder surgery
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-04)
<p><i>Background - </i>Interscalene brachial plexus block is currently the gold standard for intra‐ and post‐operative pain management for patients undergoing arthroscopic shoulder surgery. However, it is associated with block related complications, of which effect on the phrenic nerve have been of most interest. Side effects caused by general anesthesia, when this is required, are also a concern. ...
Polymorphisms in the vitamin D system and mortality - The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-18)
Vitamin D deficiency is associated with diabetes, cancer, immunological and cardiovascular diseases as well as increased mortality. It has, however, been difficult to show a causal relation in randomized, controlled trials. Mendelian randomization studies provide another option for testing causality, and results indicate relations between the serum 25-hydroxyvitamin D (25(OH)D) level and some diseases, ...
Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-15)
<i>Background</i>: High triglycerides and low levels of high density lipoprotein (HDL)-cholesterol are observed to
promote tumor growth. However, whether breast cancer heterogeneity may explain the contradictory influence of
triglycerides and cholesterol observed on breast cancer prognosis remains unclear.<p>
<p><i>Methods</i>: A population-based survival study among 464 breast cancer cases ...