• Chemical and Enzyme-Assisted Extraction of Fucoidan from two Species of Brown Macroalgae (Ascophyllum nodosum and Saccharina latissima) 

      Maribu, Ingrid (Master thesis; Mastergradsoppgave, 2021-05-18)
      Marine environments contain half of the global biodiversity and are a major source of bioactive compounds. Macroalgae are vital species in marine ecosystems and are known to produce several bioactive compounds and polysaccharides that possesses several bioactivities. These molecules are traditionally extracted using methods that heavily rely on hazardous solvents and heat, that more importantly ...
    • CO2 i sjø og på land. En lokal studie med fokus på fabrikkrøyk og miljø. 

      Øyen, Frode Jacobsen (Master thesis; Mastergradsoppgave, 2019-11-15)
      Netto utslipp av karbon til atmosfæren har økt siden starten på den industrielle revolusjon. Rundt halvparten av karbon som slippes ut blir tatt opp av havet fysisk via karbon fluks eller bundet opp i økosystemer i havet eller på land. Denne oppgaven tolker og diskuterer potensielle lokale virkninger av industriell CO2 utslipp ved å benytte fysiske og biologiske, oseanografi og CO2 data samlet ...
    • A Comparison of Biochemical Composition and Bioactivity of Abalone (Haliotis spp) Subjected to Different Diets and Treatments 

      Opara, Uchenna Ben (Master thesis; Mastergradsoppgave, 2021-03-01)
      The fast growth of the aquaculture sector has led to an unsustainable harvest of wild fish species used in the production of aquaculture feed. Integrated Multi-trophic Aquaculture (IMTA) promises ecological and socio-economic advantages that include the provision of sustainable aquaculture feed. However, the promotion of IMTA requires that the stakeholders have sufficient quantitative information ...
    • Design av en transkripsjonssensor i Escherichia coli : til deteksjon av virkningsmåten til nyoppdagede antimikrobielle peptider 

      Bjørsvik, Magnus Støback (Master thesis; Mastergradsoppgave, 2013-05-15)
      Antibiotikaresistens er vurdert som den største trusselen knyttet til behandling av de smittsomme sykdommene i den vestlige verden, på grunn av økningen i infeksjoner som følge av multiresistente bakterier. Nylige sykdomsutbrudd forårsaket av bakterier med total eller delvis resistens mot tilgjengelige antibiotika, kan være meget alvorlige siden mulighetene for behandling er svært begrenset. Marin ...
    • The effect of microplastic on natural transformation and biofilm formation using Acinetobacter baylyi as a model organism 

      Strømmen, Marte (Master thesis; Mastergradsoppgave, 2022-05-15)
      Microplastic pollution is a big and rapidly increasing environmental problem in the world. Although the direct effects of microplastic pollution are well-studied the indirect effects are hardly investigated, especially in the context of spreading antibiotic resistance genes. Antibiotic resistance is a natural phenomenon, but the misuse and overuse of antibiotics has led to a rapid development and ...
    • Effekter på bakteriesamfunn av boreslamdeponering på havbunnen 

      Øverleir, Ida Maylen (Master thesis; Mastergradsoppgave, 2014-05-15)
      Som en del av Barents Sea Drill Cuttings Research Initiative (BARCUT) fokuserte denne masteroppgaven på å avdekke om bakteriesammensetningen i sedimentet rundt en borebrønn påvirkes av boreavfallsdeponeringer. Under tokt med M/S «Njord Viking» 30. november – 3. desember 2013 ble det hentet opp kjerneprøver ved en letebrønn i Brønnlokaliteten. Dette ble gjort samtidig med at Akvaplan-niva gjennomførte ...
    • Enzymatic protein hydrolysis of residual raw material from Atlantic cod: Selectivity of proteases, outcome and bioactivities 

      Sorokina, Liudmila (Master thesis; Mastergradsoppgave, 2020-08-14)
      Global trends show that interest in fish products and fish consumption are increasing, while marine fishery resources are decreasing. Fish processing industry produces a high amount of residual raw materials that have nutritious proteins and other valuable compounds. An optimization of residual raw materials’ utilization can help meet the growing demand for fish products and help reduce environmental ...
    • Exploring the antibacterial and anticancer potential of five marine fungi. With the use of OSMAC-approach 

      Bragmo, Hanne (Master thesis; Mastergradsoppgave, 2017-05-15)
      The marine environment is an untapped source for biodiversity and has a great potential to provide the drugs of the future. Antibiotic resistance is an increasing threat worldwide and the need for discovering new antibacterial compounds is urgent. Marine microorganisms produce a wide range of bioactive compounds, and marine fungi have only been exploited to a small extent. This creates a great ...
    • Exploring the Biotechnological Potential of the Secretome from the Marine Fungus Digitatispora marina Proteomics, Bioinformatics and Heterologous Expression of Novel Proteases 

      Heimland, Elise Nilsen (Master thesis; Mastergradsoppgave, 2022-05-16)
      Cold-adapted enzymes are of biotechnological value due to their high catalytic powers at low to moderate temperatures and their high thermolability at elevated temperatures. Marine fungi are an understudied group of organisms, which makes them interesting as enzyme producers because of their adaptions to marine habitats. In this thesis study, a bioprospecting pipeline was constructed, and different ...
    • Exploring the potential of two arctic marine bacteria for the production of bioactive metabolites 

      Jenssen, Marte (Master thesis; Mastergradsoppgave, 2017-05-15)
      The number of compounds being isolated from the marine environment is increasing, and there is a great potential for discovering new marine derived drug candidates. Improved collection techniques has strengthened bioprospecting on a wider diversity of marine microorganisms. The focus on microorganisms has led to the realisation that many of the natural products originally isolated from macroorganisms, ...
    • Expression of Secondary Metabolite Gene Clusters and Production of Secondary Metabolites in Three Nostoc strains Subjected to Deprivation on Nutrients and Competition 

      Wilhelmsen, Oda Sofie Bye (Master thesis; Mastergradsoppgave, 2019-05-15)
      Cyanobacteria are a unique source of natural products, where most of them are synthesized by non-ribosomal peptide synthase, polyketide synthase, or a hybrid of these pathways. The identification of such biosynthetic genes responsible for the production of secondary metabolites is still a relatively unexplored area, and it remains many natural products for which a biosynthetic origin is unknown. ...
    • From Lab to Industry - Enzymes from Undifferentiated Marine Rest Raw Material 

      Steinsholm, Silje (Master thesis; Mastergradsoppgave, 2014-05-15)
      The aim of this project was to optimize the extraction of esterase enzymes from undifferentiated herring rest raw material. This was conducted by comparing, in laboratory scale, the outcome of using homogenised and non-homogenised raw material, and by extracting with buffers of different pH. Further on, clarification experiments of flocculation were performed on the optimal extract. The focus was ...
    • Genomic characterization and insights of local adaptation in Norwegian juvenile lumpfish populations 

      Granviken, Emilie Østby (Master thesis; Mastergradsoppgave, 2021-05-18)
      The lumpfish (Cyclopterus lumpus Linnaeus, 1758) has for many years been an attractive target for the roe fisheries in Norway and has more recently become an important cleanerfish in the salmonid farming industry for the control of salmon lice (Copepoda: Caligidae). Despite this, there is a lack of knowledge about several life aspects of the species and studies on its genetic structure have been ...
    • Impact of CRISPR/Cas9 on the expressions of selected immune genes in salmonid cells 

      Palerud, Jocelyn Hernandez (Master thesis; Mastergradsoppgave, 2023-07-05)
      The discovery of CRISPR/Cas9 as a gene editing tool has revolutionized the field of molecular biology due to its huge potential for innovative applications. However, the biosafety concerns on CRISPR/Cas9-mediated gene editing like off-target mutations, triggering of cell death, and induction of cellular stress need to be elucidated. This thesis aims to investigate the impacts of electroporation ...
    • Isolation and characterisation of secondary metabolites from arctic, marine invertebrates 

      Glomsaker, Eirin (Master thesis; Mastergradsoppgave, 2017-05-15)
      Bioprospecting is the systematic search for and discovery of products in nature, with the purpose of developing commercial products. The marine environment displays a rich biological diversity, as well as a diversity within environmental factors. This environment has necessitated the production of potent secondary metabolites by marine organisms in their arms race against predators and pathogens, ...
    • Isolering av etylester og triacylglyserol ved hjelp av fast fase ekstraksjon 

      Guldberg, Mia Brattli (Master thesis; Mastergradsoppgave, 2018-05-15)
      I de siste par tiårene har det vært en kraftig økning i humant bruk av kosttilskudd som inneholder langkjedede omega-3 fettsyrer, det vil si eicosapentaensyre (EPA) og docosaheksaensyre (DHA). Årsaken er de antatte positive helseeffekter disse fettsyrene har. I dag er det vanligst at slike kosttilskudd tas i form av kapsler, blant annet fordi mange mennesker synes marine oljer er ubehagelig å drikke ...
    • Manipulating the Epigenetic Machinery of Marine Fungi Through the Application of Epigenetic Modifiers to Induce the Biosynthesis of Novel Secondary Metabolites 

      Marø, Cathrine Eiken (Master thesis; Mastergradsoppgave, 2020-05-15)
      Fungi are among the most prolific producers of secondary metabolites, many of which have huge utility for society as various anti-infective and anticancer drugs. The genes encoding these secondary metabolites are arranged in continuous biosynthetic gene clusters (BGCs). Each fungus can have tens of different BGCs in its genome, possessing the ability to produce a multitude of secondary metabolites ...
    • Mikrobiell stabilitet og kjemisk sammensetning i hydrolysat fra Calanus finmarchicus 

      Jørstad, Torunn Johansen (Master thesis; Mastergradsoppgave, 2015-05-15)
      Calanus finmarchicus (raudåte) er den mest tallrike av alle marine skalldyrarter, med en stående bestand på cirka 70-80 millioner tonn i det Nordiske hav. Siden ny bærekraftig innhøstingsteknologi er utviklet for arten, er det mulig å utnytte denne ressursen kommersielt. I dag produseres olje fra C. finmarchicus, og har flere dokumenterte helseeffekter. Ved produksjon framstilles fire ganger mer ...
    • Mikrobiota hos grønn kråkebolle, Strongylocentrotus droebachiensis. Fokus på identifikasjon av bakteriestammer 

      Bentdal, Solveig (Master thesis; Mastergradsoppgave, 2017-05-15)
      It has been reported that the green sea urchin, Strongylocentrotus droebachiensis, can be affected by symptoms that is associated with the disease called “bald sea urchin disease”. However, no pathogen for sea urchins are known in the literature, but a working hypothesis claims that species of the Vibrio splendidus clade can be associated with symptoms characterized as bald sea urchin disease in S. ...
    • Modeling the "microbial chassis effect" on the performance of a genetic switch 

      Verusevski, Vanja (Master thesis; Mastergradsoppgave, 2022-03-21)
      Escherichia coli is one of the most established bacterial hosts for genetic devices, partially due to the available knowledge and tools for ease of manipulation. However, there is an incentive to increase the current number of available recipients. For instance, marine bacteria are being recognized for their potential as microbial "chassis" due to their rich genetic and metabolic diversity. With ...