• The Cafeteria Diet: a standardized protocol and its effects on behavior 

      Lalanza, Jaume F; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-10)
      Obesity is a major health risk, with junk food consumption playing a central role in weight gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet model for animal experiments consists of the same tasty but unhealthy food products that people eat (e.g. hot dogs and muffins), and considers variety, novelty and secondary food features, such as smell and texture. ...
    • CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state 

      Huijgens, Patty Thalia; Heijkoop, Roy; Vanderschuren, Louk; Lesscher, Heidi; Snoeren, Eelke Mirthe Simone (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-24)
      This study aims to investigate the underlying neurobiological mechanisms that regulate natural reward seeking behaviors, specifically in the context of sexual behavior and sucrose self-administration. The role of CaMKIIa+neurons in the bed nucleus of the stria terminalis (BNST) was explored using chemogenetic silencing and -stimulation. Additionally, the study examined how these effects ...
    • Can a happy relationship predict a happy life? A population-based study of maternal well-being during the life transition of pregnancy, infancy, and toddlerhood 

      Dyrdal, Gunvor Marie; Røysamb, Espen; Nes, Ragnhild Bang; Vittersø, Joar (Journal article; Tidsskriftartikkel; Peer reviewed, 2010-12-12)
      The association between overall life satisfaction (LS) and relationship satisfaction (RS) was investigated longitudinally among mothers (N=67,355), using data from the Norwegian Mother and Child Cohort Study (MoBa), conducted by the Norwegian Institute of Public Health. Data were collected twice during pregnancy, and at 6 and 36 months postpartum. Satisfaction increased during pregnancy, with RS ...
    • Can accelerated transcranial direct current stimulation improve memory functions? An experimental, placebo-controlled study 

      Bystad, Martin; Storø, Benedicte Haug; Gundersen, Nina; Larsen Wiik, Ida Karine; Nordvang, Lene; Grønli, Ole; Rasmussen, Ingrid Daae; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-01)
      The aim of this study was to investigate whether transcranial Direct Current Stimulation (tDCS) could improve verbal memory functions in healthy old and younger participants. We hypothesized that active tDCS led to significantly improved memory function, compared to placebo tDCS. Forty healthy participants (20 old and 20 younger participants) were included in the study. We applied a novel stimulation ...
    • Can Difficult Lectures be Interesting AND Pleasant? Hedonic and Eudaimonic Feelings as a Function of Perceived Difficulty 

      Ivan, Håvard (Master thesis; Mastergradsoppgave, 2022-12-01)
      What is it that makes challenge and complexity so appealing to humans? Research derived from positive psychology have tried to answer this question, and in the process found evidence suggesting that people experience different feelings as the perception of difficulty rises. In this study, using Gudrun Eckblad’s scheme theory as premise, we predicted that reported feelings of pleasure would be most ...
    • Can drug-related information reverse the effects of a local anesthetic cream? An investigation into the nocebo hyperalgesic response 

      Zwarg, Maria Lorentze; Hage Eilertsen, Hans-Ingvald (Master thesis; Mastergradsoppgave, 2013-04-30)
      Objective: Verbal information accompanying administration of a drug has been shown to modulate treatment outcome, in both positive and negative directions. If drug effects alter as a function of verbal suggestions, negative information may potentially abolish or even reverse treatment effects. To test whether nocebo information can reverse the effect of a drug, we investigated how such information ...
    • Can HRV Biofeedback Improve Short-Term Effort Recovery? Implications for Intermittent Load Sports 

      Perez-Gaido, Mauro; Lalanza, Jaume F; Parrado, Eva; Capdevila, Lluis (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-05)
      As intensity and physical demands continue to rise in sport competition, faster and better recovery becomes essential. The aim of this study was to assess the effects of HRV biofeedback (HRVB) while recovering from a submaximal aerobic exercise. Ten physically-active graduate students participated in the study, which was conducted in four sessions: exercise with free-breathing recovery, first ...
    • Can perinatal SSRI exposure affect sexual behavior later in life? Early Developmental Fluoxetine Exposed Female Rats Observed in a Seminatural Environment 

      Hegstad, Jan (Master thesis; Mastergradsoppgave, 2019-05-02)
      Renewed interests in sexual behavior research stems from human reports of negative symptoms of selective serotonin reuptake inhibitor (SSRI). The use of SSRIs, during pregnancy might impact the developing child, due to the drug’s ability to cross the placenta and also be present in breastmilk. Perinatal SSRI exposure thus elevates serotonin levels in the developing brain, during phases where serotonin ...
    • The case of case reports: A decade of publications by staff at a major university hospital 

      Nissen, Trygve; Bergvik, Svein; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      <p><i>Rationale:</i> The place of case reports in the medical literature has been much debated in recent years. This study was undertaken to gain knowledge about the publication practice of case reports and case series from a major university hospital. <p><i>Method:</i> We decided to conduct a retrospective, bibliographic, descriptive study of published case reports and case series from a university ...
    • The Category-Focus Implicit Association Test 

      Siebler, Frank; González, Roberto; Ordóñez, Gabriela; Bohner, Gerd; Haye, Andrés; Sirlopú, David; Millar, Andres; De Tezanos-Pinto, Pablo; Torres, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Causes and consequences of stress. Interplay between cognitive social and biological aspects 

      Nolen, Kristi Shannon (Master thesis; Mastergradsoppgave, 2015-11-03)
      The purpose of this article is to explore the roles of cognitive, social and biological reasons for stress and to relate practical interventions to them. Understanding stress and how it can play out is pivotal in managing it. The physiological stress response works much in the same manner in individuals everywhere; first observing something that is potentially perceived as a threat to the self, and ...
    • Cerebral cortical thickness and surface area in adolescent anorexia nervosa: Separate and joint analyses with a permutation-based nonparametric method 

      Myrvang, Anna Dahl; Vangberg, Torgil Riise; Stedal, Kristin; Rø, Øyvind; Endestad, Tor; Rosenvinge, Jan H; Aslaksen, Per M (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-17)
      <i>Objective</i> - Reduction in cerebral volume is often found in underweight patients with anorexia nervosa (AN), but few studies have investigated other morphological measures. Cortical thickness (CTh) and surface area (CSA), often used to produce the measure of cortical volume, are developmentally distinct measures that may be differentially affected in AN, particularly in the developing brain. ...
    • Cerebrale volumetriske endringer hos jenter med anorexia nervosa 

      Eriksen, Mie-Susanne Høeg (Master thesis; Mastergradsoppgave, 2017-05-01)
      Tidligere studier som har undersøkt hjernens strukturelle og funksjonelle karakteristikker hos pasienter med Anorexia nervosa (AN), har vist korrelasjoner mellom AN og svekkelse i eksekutive funksjoner, og mellom AN og volumetriske mål av hjernen. I denne studien var hensikten å undersøke om det er volumetriske forskjeller i hjernen kortikalt og subkortikalt, mellom pasientgruppen (AN-pasienter) og ...
    • Cerebrospinal fluid markers for synaptic function and Alzheimer type changes in late life depression 

      Siafarikas, Nikias Ioannis; Kirsebom, Bjørn-Eivind; Srivastava, Deepak P; Eriksson, Cecilia Magdalena; Auning, Eirik; Hessen, Erik; Selbæk, Geir; Blennow, Kaj; Aarsland, Dag; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-13)
      To explore markers for synaptic function and Alzheimer disease (AD) pathology in late life depression (LLD), predementia AD and normal controls (NC). A cross-sectional study to compare cerebrospinal fluid (CSF) levels of neurogranin (Ng), Beta-site amyloid-precursor-protein cleaving enzyme1 (BACE1), Ng/BACE1 ratio and Amyloid-β 42/40 ratio, phosphorylated-tau and total-tau in LLD with (LLD AD) or ...
    • Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults 

      Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Rongve, Arvid; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)
      Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a marker of neuronal body injury) and neurofilament light chain (NfL, a marker of axonal injury) show age-related increases in normal aging. In the current study, we aimed to investigate ...
    • Cerebrospinal fluid neurogranin/β-site APP-cleaving enzyme 1 predicts cognitive decline in preclinical Alzheimer's disease 

      Kirsebom, Bjørn-Eivind; Nordengen, Kaja; Selnes, Per; Waterloo, Knut; Torsetnes, Silje Bøen; Gísladóttir, Berglind; Brix, Britta; Vanmechelen, Eugeen; Bråthen, Geir; Hessen, Erik; Aarsland, Dag; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-10)
      <i>Introduction</i>: The cerebrospinal fluid neurogranin (Ng)/β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) ratio may reflect synaptic affection resulting from reduced beta-amyloid (Aβ) clearance. We hypothesize that increased Ng/BACE1 ratio predicts the earliest cognitive decline in Alzheimer’s disease.<p> <p><i>Methods</i>: We compared Ng/BACE1 levels between cases with subjective ...
    • Change in physical activity is not associated with change in mental distress among adolescents: The Tromsø Study: Fit Futures 

      Opdal, Ida Marie; Morseth, Bente; Handegård, Bjørn Helge; Lillevoll, Kjersti; Ask, Helga; Nielsen, Christopher Sivert; Horsch, Alexander; Furberg, Anne-Sofie; Rosenbaum, Simon; Rognmo, Kamilla (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-09)
      <i>Background</i>: Previous research shows that physical activity has a protective effect on mental distress in adults, but the relationship is less researched and seems more ambiguous for adolescents. Studies in this field have typically been cross-sectional by design and based on self-reported physical activity measures, which are known to be vulnerable to response bias. The aim of this study ...
    • Changes in reward-induced neural activity upon Cafeteria Diet consumption 

      Heijkoop, Roy; Ferrer Lalanza, Jaume; Solanas, Montserrat; Álvarez-Monell, Adam; Subias-Gusils, Alex; Escorihuela, Rosa; Snoeren, Eelke Mirthe Simone (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-01)
      Excessive consumption of highly palatable foods rich in sugar and fat, often referred to as “junk” or “fast” foods, plays a central role in the development of obesity. The highly palatable characteristics of these foods activate hedonic and motivational mechanisms to promote food-seeking behavior and overeating, which is largely regulated by the brain reward system. Excessive junk food consumption ...
    • Childhood Sensorineural Hearing Loss and Divorce in a Large Norwegian Cohort: Results from the HUNT Study 

      Idstad, Mariann; Rognmo, Kamilla; Engdahl, Bo Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-10)
      The aim of this study is to investigate the association between childhood sensorineural hearing loss (CSNHL) and divorce in a large, Norwegian cohort. Data from the School Hearing Investigation in Nord-Trøndelag (SHINT), Norway, are combined with registry data on marital status from Statistics Norway and matched controls from the Nord-Trøndelag Health Study (HUNT). The sample includes a total of ...
    • Childhood trauma and outcome trajectories in patients with longstanding eating disorders across 17 years 

      Eielsen, Hanna Kristine Punsvik; Ulvenes, Pål Gunnar; Hoffart, Asle; Rø, Øyvind; Rosenvinge, Jan Harald; Vrabel, KariAnne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-27)
      Background: A large proportion of patients with eating disorders (ED) report experiences of childhood trauma. Latent trajectory analysis in ED samples reveals the complexities in course and outcome and can explore the long-term impact of adverse experiences in childhood.<p> <p>Method: A total of 84 patients with longstanding ED were included. ED symptoms were assessed by the Eating Disorder ...