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Effects of transcranial direct current stimulation for treating depression: A modeling study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-28)
<p><i>Background</i>:
Transcranial direct current stimulation (tDCS) above the left dorsolateral prefrontal cortex (lDLPFC) has been widely used to improve symptoms of major depressive disorder (MDD). However, the effects of different stimulation protocols in the entire frontal lobe have not been investigated in a large sample including patient data.</p>
<p><i>Methods</i>:
We used 38 head ...
Blinding is compromised for transcranial direct current stimulation at 1 mA for 20 min in young healthy adults
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-19)
Transcranial direct current stimulation (tDCS) is a non‐invasive brain stimulation method that is frequently used to study cortical excitability changes and their impact on cognitive functions in humans. While most stimulators are capable of operating in double‐blind mode, the amount of discomfort experienced during tDCS may break blinding. Therefore, specifically designed sham stimulation protocols ...
Commentary: Transcranial stimulation of the frontal lobes increases propensity of mind-wandering without changing meta-awareness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-05)
A Commentary on <p>
<p>Transcranial stimulation of the frontal lobes increases propensity of mind-wandering without changing meta-awareness<p>
<p>by Axelrod, V., Zhu, X., & Qui, J. (2018). <i>Scientific Reports</i>, 8:15975. doi: 10.1038/s41598-018-34098-z
The interplay between executive control, behavioral variability and mind wandering: Insights from a high-definition transcranial direct-current stimulation study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-21)
While the involvement of executive processes in mind wandering is largely undebated, their exact relationship is subject to an ongoing debate and rarely studied dynamically within‐subject. Several brain‐stimulation studies using transcranial direct current stimulation (tDCS) have attempted to modulate mind‐wandering propensity by stimulating the left dorsolateral prefrontal cortex (DLPFC) which is ...
Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved]
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-06)
During the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized ...
Probing the neural signature of mind wandering with simultaneous fMRI-EEG and pupillometry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-01)
Mind wandering reflects the shift in attentional focus from task-related cognition driven by external stimuli toward self-generated and internally-oriented thought processes. Although such task-unrelated thoughts (TUTs) are pervasive and detrimental to task performance, their underlying neural mechanisms are only modestly understood. To investigate TUTs with high spatial and temporal precision, we ...
High-Definition Transcranial Direct Current Stimulation Improves Delayed Memory in Alzheimer’s Disease Patients: A Pilot Study Using Computational Modeling to Optimize Electrode Position
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-14)
Background: The optimal stimulation parameters when using transcranial direct current stimulation (tDCS) to improve memory performance in patients with Alzheimer’s disease (AD) are lacking. In healthy individuals, inter-individual differences in brain anatomy significantly influence current distribution during tDCS, an effect that might be aggravated by variations in cortical atrophy in AD ...