Super-resolution optical microscopy, commonly referred to as optical nanoscopy, has enabled imaging of biological samples with a resolution that was only achievable previously using electron microscopy. Optical nanoscopy is a rapidly growing field, with several different techniques and implementations that overcome the diffraction limit of light. However, the common nanoscope continues to be a rather ...

The evanescent field on top of optical waveguides is used to image membrane network and sieve-plates of liver endothelial cells. In waveguide excitation, the evanescent field is dominant only near the surface (~100-150 nm) providing a default optical sectioning by illuminating fluorophores in close proximity to the surface and thus benefiting higher signal-to-noise ratio. The sieve plates of liver ...

Present optical nanoscopy techniques use a complex microscope for imaging and a simple glass slide to hold the sample. Here, we demonstrate the inverse: the use of a complex, but mass-producible optical chip, which hosts the sample and provides a waveguide for the illumination source, and a standard low-cost microscope to acquire super-resolved images via two different approaches. Waveguides composed ...

This report gives a complete record of all data sets that were collected during the CIRFA cruise 22 April - 9 May 2022, with RV Kronprins Haakon, to the western Fram Strait and the East Greenland Sea. IMR cruise ID 2022704. The CIRFA-cruise 2022 was funded by UiT the Arctic University of Norway, the European Space Agency (RFP Response No 3-17845), the Research Council of Norway (RCN project ...

Ultrasound based structural health monitoring of piezoelectric material is challenging if a damage changes at a microscale over time. Classifying geometrically similar damages with a difference in diameter as small as 100 m is difficult using conventional sensing and signal analysis approaches. Here, we use an unconventional ultrasound sensing approach that collects information of the entire ...

Deep learning-based approaches for content-based image retrieval (CBIR) of computed tomography (CT) liver images is an active field of research, but suffer from some critical limitations. First, they are heavily reliant on labeled data, which can be challenging and costly to acquire. Second, they lack transparency and explainability, which limits the trustworthiness of deep CBIR systems. We address ...

The ice sheet model intercomparison project for CMIP6 (ISMIP6) effort brings together the ice sheet and climate modeling communities to gain understanding of the ice sheet contribution to sea level rise. ISMIP6 conducts stand-alone ice sheet experiments that use space- and time-varying forcing derived from atmosphere–ocean coupled global climate models (AOGCMs) to reflect plausible trajectories for ...

Two basis sets-a large and a small one-are associated with each nucleus of the system. Each atom has its own separate one-electron basis comprising the large basis set of the atom in question and the small basis sets for the partner atoms in the complex. The perturbed atoms in molecules and solids model is at core of the approach since it allows for the definition of perturbed atoms in a system. It ...

Comets, comet-like objects and their fragments are the most plausible source for the dust in both the inner heliosphere and planetary debris discs around other stars. The smallest size of dust particles in debris discs is not known and recent observational results suggest that the size distribution of the dust extends down to sizes of a few nanometres or a few tens of nanometres. In the Solar System, ...

The manipulation and understanding of molecular transport across functionalized nanopores will take us closer to mimicking biological membranes and thus to design high-performance permselective separation systems. In this work, Surface-initiated atom transfer radical polymerization (SI-ATRP) of (2-methacryloyloxy)-ethyltrimethylammonium chloride (METAC) was performed on both mesoporous silica and ...