Recent additions

  • Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene 

    Emblem, Åse; Knutsen, Erik; Jørgensen, Tor Erik; Fure, Hilde; Johansen, Steinar Daae; Brekke, Ole Lars; Mollnes, Tom Eirik; Karlsen, Bård Ove (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-29)
    Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat invading microorganisms. Understanding the expression of long non-coding RNAs containing Alu elements in inflammation is important for reconstructing ...
  • Increased autonomy with capacity-based mental health legislation in Norway: a qualitative study of patient experiences of having come off a community treatment order 

    Wergeland, Nina Camilla; Fause, Åshild; Weber, Astrid; Riley, Henriette (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-07)
    Background: Capacity-based mental health legislation was introduced in Norway on 1 September 2017. The aim was to increase the autonomy of patients with severe mental illness and to bring mental health care in line with human rights. The aim of this study is to explore patient experiences of how far the new legislation has enabled them to be involved in decisions on their treatment after they ...
  • Identity construction in medical student stories about experiences of disgust in early nursing home placements: A dialogical narrative analysis 

    Warmington, Sally; Johansen, May-Lill; Wilson, Hamish (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-17)
    Objectives To explore medical students’ reflective essays about encounters with residents during preclinical nursing home placements.<p> <p>Design Dialogical narrative analysis aiming at how students characterise residents and construct identities in relation to them. <p>Setting Medical students’ professional identity construction through storytelling has been demonstrated in contexts including ...
  • Modifiable and non-modifiable risk factors in hip fracture mortality in Norway, 2014 to 2018 - a linked multiregistry study 

    Kjærvik, Cato; Gjertsen, Jan-Erik; Stensland, Eva; Saltete-Benth, Jurate; Søreide, Odd (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
    Aims<p> <p>This study aimed to identify risk factors (patient, healthcare system, and socioeconomic) for mortality after hip fractures and estimate their relative importance. Further, we aimed to elucidate mortality and survival patterns following fractures and the duration of excess mortality. <p>Methods<p> Data on 37,394 hip fractures in the Norwegian Hip Fracture Register from January 2014 to ...
  • Optimizing medication therapy in older hospitalized patients. Identifying potentially inappropriate medications and testing an interdisciplinary intervention 

    Johansen, Jeanette Schultz (Doctoral thesis; Doktorgradsavhandling, 2022-08-26)
    The overall aim of this thesis is to provide knowledge on potentially inappropriate medications (PIMs) in hospitalized older patients and to investigate how clinical pharmacist services in an interdisciplinary setting can contribute to medication optimization and improve patient outcomes. First, we used national health registers to investigate how admissions to Norwegian geriatric hospital wards ...
  • Digital learning application for clinical dentistry – a pilot study 

    Ertsås, Oliver; Marjala, Matias Fosse (Master thesis; Mastergradsoppgave, 2022-05-02)
    <p>Background: Microlearning is a growing trend in education which can have a positive effect on learning motivation and outcome. In health education, it has been shown to increase student knowledge and confidence in clinical procedures. Little research has been done on implementing digital learning solutions specifically aimed for clinical dental studies. Unifractal is an existing digital learning ...
  • Folkehelseperspektivet i kommunalt arbeid med bærekraftmålene – En komparativ case-studie av styringsdokumenter i to norske kommuner 

    Aarethun, Vilde (Master thesis; Mastergradsoppgave, 2022-06-14)
    FNs bærekraftmål representerer en ny milepæl i det globale arbeidet med bærekraftig utvikling, og kommunene og fylkeskommunene er utpekt til nøkkelaktører for å realisere bærekraftmålene og en bærekraftig samfunnsutvikling i Norge. Flere studier viser imidlertid at begreper både relatert til folkehelse og bærekraft kan oppleves utfordrende å implementere og operasjonalisere i lokalt planverk når det ...
  • The experience of dependence on homecare among people ageing at home 

    Martinsen, Bente; Norlyk, Annelise; Gramstad, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-09)
    Being dependent on homecare potentially threatens a person’s integrity and autonomy, particularly when people are dependent on help to manage basic bodily functions that involve intimacy and nudity, making the person vulnerable despite being in his or her own home. As the population continues to age and live longer, more people are expected to be dependent on homecare. The aim of this study was ...
  • Capturing minds. Towards a methods critique of questionnaire-based mental health surveys. 

    Wackers, Ger; Schille-Rognmo, Marthe (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-29)
    Mental health surveys of general populations use psychometric instruments derived from psychiatric symptom checklists and assessment scales. Mental health surveys of this type have become so ubiquitous and influential that the psychometric methods that are at the heart of them seem to be beyond reproach. Are these the right tools to do the job of capturing the minds of general populations? This ...
  • Ultrasound assessed carotid atherosclerosis in a general population : the Tromsø study 

    Joakimsen, Oddmund (Doctoral thesis; Doktorgradsavhandling, 2000)
    As a neurologist with a special interest in cerebrovascular diseases, and with several years of practice with ultrasound examinations of extra- and intracranial arteries, I have some times experienced patients in whom ultrasound revealed unexpected findings which surprised mc, and made me wonder about etiological relationships and clinical implications. Thus, ultrasound examinations of the carotid ...
  • How life events are perceived to link to bodily distress: A qualitative study of women with chronic pelvic pain. 

    Boge-Olsnes, Cathrine Maria; Risør, Mette Bech; Øberg, Gunn Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-28)
    Chronic pelvic pain (CPP) is highly prevalent among women and the condition is poorly understood. In addition to multiple symptoms from the pelvis, CPP patients frequently suffer bodily distress like musculoskeletal pain and negative emotional, behavioral, and sexual implications. This paper is based on a qualitative study including semi-structured interviews with eight women with CPP. Our project ...
  • Boundary work in task-shifting practices – A qualitative study of reablement teams 

    Eliassen, Marianne; Moholt, Jill-Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)
    Background - Health services worldwide have provided incentives for establishing teams to accommodate complex health care tasks, enhance patient outcomes and organizational efficiency, and compensate for shortages of health care professionals. Parallel to and partly due to the increased focus on teamwork, task shifting has become a health policy. Task shifting involves new tasks and responsibilities, ...
  • Novel screening methods for nanoscale changes in liver cell fenestrations elicited by pharmaceuticals 

    Szafranska, Karolina (Doctoral thesis; Doktorgradsavhandling, 2022-08-19)
    This thesis focuses on liver sinusoidal endothelial cells (LSEC) and one of their characteristic features called fenestrations. LSEC line the hepatic sinusoids and filter solutes from the plasma. The bidirectional transport of solutes between the bloodstream and the interior of the liver is facilitated via transcellular nanopores called fenestrations. Fenestrations are dynamic structures with diameters ...
  • Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome 

    Winkler, Juliane; Liu, Pengyuan; Phong, Kiet; Hinrichs, Johanna H.; Ataii, Nassim; Williams, Katherine; Hadler-Olsen, Elin Synnøve; Samson, Susan; Gartner, Zev J.; Fisher, Susan; Werb, Zena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-09)
    Environmental chemicals such as bisphenol A (BPA) are thought to contribute to carcinogenesis through their endocrine-disrupting properties. Due to accumulating evidence about negative human health effects, BPA is being phased out, but in parallel, exposures to replacement chemicals such as bisphenol S (BPS) and bisphenol F (BPF) are increasing. Little is known about their biologic effects, but ...
  • Dental plaque and gingival bleeding in adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis 

    Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Lie, Stein Atle; Rygg, Marite; Fischer, Johannes; Rosén, Annika; Bletsa, Athanasia; Luukko, Keijo Aukusti; Shi, Xie-Qi; Halbig, Josefine Mareile; Frid, Paula Hanna Therese; Cetrelli, Lena Elisabet; Tylleskär, Karin; Rosendahl, Karen; Skeie, Marit Slåttelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
    Objective - To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes.<p ...
  • Occupational cold exposure is associated with neck pain, low back pain, and lumbar radiculopathy 

    Stjernbrandt, Albin; Farbu, Erlend Hoftun (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-24)
    Ambient cold exposure can pose health risks, and this study was aimed at investigating associations with musculoskeletal disorders. A postal survey was performed on 12,627 men and women, ages 18–70 years, living in northern Sweden. Statistical associations were determined using multiple logistic regression. The study sample consisted of 6,886 women (54.5%), and 5,741 men. Reporting high occupational ...
  • Targeting Internalizing Symptoms in Children: What is the Impact on School Functioning? 

    Pedersen, Marit Løtveit; Holen, Solveig; Sund, Anne Mari; Adolfsen, Frode; Løvaas, Mona Elisabeth S; Martinsen, Kristin; Neumer, Simon-Peter; Patras, Joshua; Rasmussen, Lene-Mari Potulski; Lydersen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-13)
    Internalizing problems may be associated with poor academic performance and school absenteeism among youth. This study investigated the impact of the EMOTION: “Coping Kids” Managing Anxiety and Depression Program on academic achievement and school adaptation in children. Data were collected in a national cluster-randomized controlled trial at three time points in Norway. Children (N = 688, 8–12 ...
  • “It was an important part of my treatment”: a qualitative study of Norwegian breast Cancer patients’ experiences with mainstreamed genetic testing 

    Strømsvik, Nina; Olsson, Pernilla Marie A.; Gravdehaug, Berit; Lurås, Hilde; Schlichting, Ellen; Jørgensen, Kjersti; Wangensteen, Teresia; Vamre, Tone; Heramb, Cecilie; Mæhle, Lovise Olaug; Grindedal, Eli Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-05)
    Background - In South-Eastern Norway, genetic testing for BRCA1 and BRCA2 is offered to breast cancer patients by their treating surgeon or oncologist. Genetic counselling from a geneticist or a genetic counsellor is offered only to those who test positive for a pathogenic variant or have a family history of cancer. This practice is termed “mainstreamed genetic testing”. The aim of this study was ...
  • The impact of case factors on the initial screening decision in child welfare investigations in Norway 

    Rustad, Kirsten Buck; Lauritzen, Camilla; Havnen, Karen J Skaale; Fossum, Sturla; Christiansen, Øivin; Vis, Svein Arild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-15)
    Background - When a child welfare service agency receives a report of concern, there is an initial screening to decide whether an investigation needs to be initiated. In addition to the decision maker, case factors, external factors, and organizational factors have an impact on decision making in Child Welfare Services (CWS). Few recent studies have considered the impact of case factors on the initial ...
  • Er det forskjell i behandlingsresultat mellom pasienter som besvarer spørreskjema om utfall etter nakkekirurgi og pasienter som ikke gjør det? 

    Aune, Grethe; Karlsen, Martine Eriksen (Master thesis; Mastergradsoppgave, 2020-08-05)
    Bakgrunn og formål: Oppgaven er en valideringsstudie basert på data fra Nasjonalt kvalitetsregister for rygg- og nakkekirurgi (NKR). Validiteten til kvalitetsregistre er avhengig av tilstrekkelig høy responsrate for at konklusjonene som trekkes angående effekt av en behandling skal være korrekte. Formålet med studien er å analysere om det er forskjell i behandlingsresultat mellom pasienter som ...

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