• Consumption of antibacterial agents : pharmacoepidemiology, resistance and interventions 

      Småbrekke, Lars (Doctoral thesis; Doktorgradsavhandling, 2009-09-03)
      Det overordnede målet med prosjektene som inngår i avhandlingen har vært å bidra til mer kunnskap om rasjonell bruk av antibiotika. Prosjektene er gjennomførte i allmennpraksis, og i sykehus i henholdsvis Norge, Danmark, Island og Sverige. <br>Det første delprosjektet undersøkte vi om det var mulig å endre forskrivning av antibiotika ved akutt mellomørebetennelse hos barn som kom til en legevakt. ...
    • The Murmansk county birth registry (MCBR) : the implementation and applicability of a population-based medical birth registry in the Russian Arctic 

      Anda, Erik Eik (Doctoral thesis; Doktorgradsavhandling, 2009-09-04)
      The Murmansk County Birth Registry (MCBR) was initiated on January 1. 2006. Currently (April 2009) the MCBR has registered over 26 000 births. The registry covers a geographical area known as the Kola Peninsula in Northwest Russia, which is almost entirely located above the Arctic Circle. Murmansk County is about half the size of Norway and had 857 000 inhabitants in 2008. All the 15 delivery ...
    • Diet, dietary supplements and dietary change in cancer survivors and cancer-free persons : the Norwegian Women and Cancer study and the European Prospective Investigation into Cancer and Nutrition 

      Skeie, Guri (Doctoral thesis; Doktorgradsavhandling, 2009-09-11)
      This thesis focuses on diet and dietary change in women who have breast or colorectal cancer, compared to cancer-free women in the Norwegian Women and Cancer study (NOWAC; Kvinner og kreft). The use of dietary supplements in the European Prospective Investigation into Cancer and Nutrition (EPIC) is also described. Finally, the association between use of cod liver oil and other supplements and survival ...
    • Fetal cardiac output and its distribution to the placenta and brain at 11-20 weeks of gestation 

      Vimpeli, Tommi (Doctoral thesis; Doktorgradsavhandling, 2009-09-11)
      Objective: To study some aspects of fetal heart structure and function using ultrasonography at 11-20 weeks of gestation with an emphasis on the distribution of cardiac output to the placenta and upper body including brain. <br> Methods: In a cross-sectional study of unselected pregnant population, the structure of the fetal heart was studied using transvaginal ultrasonography and feasibility ...
    • Survival and uptake of feed-derived DNA in the mammalian intestinal tract 

      Nordgård, Lise (Doctoral thesis; Doktorgradsavhandling, 2009-09-12)
      Lise Nordgård har i sin avhandling fra Universitetet i Tromsø og GenØk-Senter for biosikkerhet studert hva som skjer med introduksjon av transgene genkonstrukter som inntar en organsime via fòr. Blir DNA brutt ned når det passerer tarmkanalen eller overlever det? Kan dette DNAet passere tarmbarrierer og videre tas opp i blod og transporteres rundt i organsimen for å bli tatt opp av celler i vev? Hva ...
    • A genetic spectrum approach to affective and schizophrenic disorders : a twin- and family study 

      Edvardsen, Jack A. (Doctoral thesis; Doktorgradsavhandling, 2009-09-15)
      Over 300 eneggete- og toeggete tvillingpar rekruttert fra sykehusarkiv, og deres 1.grads slektninger (foreldre og søsken), ble intervjuet personlig og diagnostisert i henhold til moderne diagnostiske systemer (DSM-III-R) både med hensyn til symptomforstyrrelser (Akse I), og personlighetsforstyrrelser (Akse II). De ble også intervjuet angående forhold knyttet til tvillingenes fødsel og oppvekst. ...
    • Material wealth and subjective well-being 

      Biswas-Diener, Robert (Doctoral thesis; Doktorgradsavhandling, 2009-10-07)
      People have long argued over the relation of income and material well-being to happiness. A variety of studies have examined the happiness of those living at the lowest economic levels as well as those living in relatively affluent nations. Taken together, this body of research suggests that income is correlated with subjective well-being (SWB), but is neither the most important factor in happiness, ...
    • Traditional healing and the public mental health services in Sámi areas of northern Norway : interfaces and cooperation 

      Sexton, Randall Harold (Doctoral thesis; Doktorgradsavhandling, 2009-11-17)
      Dát čielggadeapmi geahččala čájehit ovttasdoaimma báikkálaš veahkehanárbevieruid ja almmolaš psykalaš dearvvašvuođabálvalusaid gaskka Finnmárkkus ja Davvi-Romssas, ja jearrá galggašii go dán guovtti vuogi gaskka leat eanet ovttasbargu. Danne geahčadit dás dárkileappot mat báikkálaš veahkehanárbevierut leat dáid sámi ja máŋggakultuvrralaš guovlluin, man ollu pasieanttat geavahit dáid, ja háliidit ...
    • Novel [18F]fluorinated prosthetic groups for the labelling of peptides for positron emission tyomography (PET) 

      Olberg, Dag Erlend (Doctoral thesis; Doktorgradsavhandling, 2009-11-20)
      Positron emission tomography is a non-invasive imaging modality allowing visualization and quantification of a wide variety of physiological and biochemical processes or of a specific lowdensity protein target. Some examples are blood flow, glucose consumption, fatty acid metabolism or detection and quantification of cell surface receptors in particular tissues. Within the spectrum of available ...
    • Some issues on provision and access to dental services in Norway 

      Abelsen, Birgit (Doctoral thesis; Doktorgradsavhandling, 2009-12-04)
      The organisation and financing of the Norwegian oral health care differ compared to general health care. The public responsibility for general health care includes the whole population, and the scope is universal coverage involving public finance, and historically public provision as well. Concerning oral health care, there seems to be less emphasis on providing the same level of service to all ...
    • Personality characteristics and vulnerability to depression : a cross-sectional and longitudinal perspective 

      Halvorsen, Marianne (Doctoral thesis; Doktorgradsavhandling, 2009-12-04)
      Depression is a serious disorder due to its highly relapsing and recurrent course, thereby highlighting the necessity to identify vulnerability factors in order to prevent and treat its course. The present thesis investigated temperament and character traits, dysfunctional attitudes, and early maladaptive schemas (EMSs) in clinically depressed (CDs), previously depressed (PDs), and never depressed ...
    • Anticancer activity of bovine lactoferricin and a cytolytic 9-mer peptide : from milk to cancer vaccine? 

      Berge, Gerd (Doctoral thesis; Doktorgradsavhandling, 2009-12-09)
      Cationic antimicrobial peptides (CAPs) are found in many diverse species playing a part in the innate immune system. CAPs are important as antimicrobial agents in most organisms, being able to kill a wide range of bacteria as well as fungi, enveloped viruses and protozoa. Certain CAPs also exhibit direct cytotoxic activity against many different types of human cancer cells. Bovine lactoferricin ...
    • Cardiovascular risk factors and risk of venous thromboembolism 

      Brækkan, Sigrid Kufaas (Doctoral thesis; Doktorgradsavhandling, 2010-01-28)
      Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a common disease, with serious short- and long-term complications and a potential fatal outcome. Despite the knowledge of several inherited and acquired risk factors for VTE, still 30-50 % of the VTE events occur in the absence of obvious predisposing factors. Traditionally, arterial and venous thrombosis has ...
    • Activity related pain in patients with musculoskeletal disorders : an explorative study 

      Damsgård, Elin (Doctoral thesis; Doktorgradsavhandling, 2010-02-26)
      Chronic musculoskeletal pain is a common health problem and a major cause for disability pension in Norway. Increased pain and fear related to general activity and exercise may be a barrier to rehabilitation of patients with chronic muscular-skeletal disorders. <br>The aim of the present research was to investigate the occurrence of activity related pain, and to explore its association with fear, ...
    • Molecular diagnosis of low intensity Schistosoma japonicum infections 

      Lier, Tore (Doctoral thesis; Doktorgradsavhandling, 2010-03-08)
      <i>Introduction:</i> <br>Schistosoma japonicum is a parasitic fluke. The adult worms live as a pair in the small mesenteric blood vessels along the intestines. The eggs are excreted in the stool. It is endemic mainly in parts of China and the Philippines with the estimated prevalence in humans exceeding a million cases. Successful control programmes have run for several decades with the result that ...
    • Living with ethical dilemmas : the ethical reasoning of surgeons and nurses in surgical units 

      Torjuul, Kirsti (Doctoral thesis; Doktorgradsavhandling, 2010-04-13)
      The aim of this thesis is to illuminate surgeons’ and nurses’ experiences of living with ethical dilemmas in their work. The thesis comprises the kinds of ethical dilemmas experienced from the practitioners’ own point of view, and explores their way of reasoning, deliberating and acting in ethically difficult situations, including the meaning they assign to their experiences. The data collection ...
    • The ACUFLASH study. Acupuncture treatment for postmenopausal hot flashes : can traditional Chinese acupuncture in addition to self-care reduce hot flash frequency and intensity, compared with self-care alone? 

      Borud, Einar Kristian (Doctoral thesis; Doktorgradsavhandling, 2010-04-16)
      Introduction. Hot flashes and night sweats are the most prevalent symptoms in menopause. Hormone therapy with oestrogen is considered the most effective treatment. However, recent research show that long term use of oestrogen increases the risk of serious adverse effects, and women and their health care providers are looking for alternatives. Acupuncture is one of the most frequently used complementary ...
    • Prognostic impact of molecular markers related to tumor proliferation and differentiation in non-smallcell lung cancer (NSCLC) 

      Al-Saad, Samer (Doctoral thesis; Doktorgradsavhandling, 2010-04-29)
      Lungekreft er krefttypen med den høyeste dødelighet av alle andre krefttyper. Hvert år får ca. 1,3 millioner mennesker av begge kjønn denne sykdommen på verdensbasis og mer enn 1,1 millioner mennesker dør av den. Det er en sterk sammenheng mellom røyking og lungekreft. Man kan få et bilde av en befolknings røykevaner ved å undersøke hyppigheten av lungekreft. For mer enn 10 år siden begynte man i ...
    • A five-year prospective follow-up of longstanding eating disorders : influence from personality disorders and child sexual abuse 

      Vrabel, KariAnne R. (Doctoral thesis; Doktorgradsavhandling, 2010-05-05)
      Follow-up studies have shown that 20-30% of patients with eating disorders develop longstanding symptoms seriously impairing their daily life. There are very few studies on the course of these patients. <br>This dissertation consists of three papers on patients admitted to a specialized inpatient treatment program at the Modum Bad psychiatric hospital. The participants were assessed upon admission, ...
    • The prognostic significance of the innate and adaptive immune systems in non-small cell lung carcinoma 

      Al-Shibli, Khalid (Doctoral thesis; Doktorgradsavhandling, 2010-05-27)
      Lungekreft er knyttet til røyking og har den høyeste dødelighet av alle andre krefttyper. Hvert år får ca. 1,3 millioner mennesker av begge kjønn denne sykdommen på verdensbasis og mer enn 1,1 millioner mennesker dør av den. En britisk analyse publisert i forskningsmagasinet Nature, bekreftet at det forskes lite på lungekreft i forhold til andre kreftformer. I analysen sto lungekreft bak 22 prosent ...