Osteoporosis is a chronic disease affecting bone tissue that may lead to fractures from minor accidents. Roughly 20% of females and 6 % of males have osteoporosis after age 50, but the disease might be present at a younger age. Early diagnosis is challenging because the disease has no symptoms. Dental radiography is a frequent examination that might be useful for early osteoporosis screening at ...

Eating disorders (EDs) are mental disorders were effective treatment may be essential for a good outcome. Previous research has shown that physical exercise and dietary therapy (PED-t) may alleviate symptoms of bulimia nervosa (BN) and binge ED (BED). The aim of this study was to explore experiences with the PED-t. We interviewed 10 therapists and 20 women who participated and analysed the transcribed ...

Effective removal of unwanted self and non-self molecules from blood is essential to keep the organism healthy. Liver sinusoidal endothelial cells (LSECs) have been shown to effectively clear such macromolecules via receptor-mediated endocytosis. The cells express several high affinity endocytosis receptors, including the mannose receptor (MR), and several scavenger receptors (SRs), which are known ...

<p><i>Background:</i> Despite recent achievements, perinatal mortality (PM) rates remain high worldwide, especially in low-income countries (>30 per 1000 births). PM is defined as the death of a fetus/livebirth between 22 completed weeks of gestation and the first 7 days of life. Simple, non-invasive interventions could reduce PM rates, since most deaths are caused by preventable conditions. Adequate ...

Abstract Background Perioperative treatment for common neurosurgical conditions such as chronic subdural hematomas (CSDH) and meningiomas vary. The perioperative period is by definition the time span from 24 hours before surgery until 30 days postoperatively. Even if the surgical treatment in the operation theater can be exactly the same, complication rates differ, and results vary. The aim of ...

<p><i>Background:</i> Persistent Organic Pollutants (POPs) are chemicals that have negative impacts on the environment and biota and have been investigated as possible risk factors for Type 2 Diabetes Mellitus (T2DM). Other well-established risk factors for T2DM, for example, obesity, increased lipids, and age have been reported to influence human POP concentrations. Previous studies have reported ...

Persistent pain is reported to be a frequent complication from surgery. Among the proposed risk factors are perioperative nerve injury and individual differences in pain sensitivity. The 6th Tromsø Study, a cross-sectional survey and medical examination, provided questionnaire data on persistent pain in general and persistent pain following surgery in particular. Participants performed tests of ...

Adolescent depression represents a substantial burden, both for the youth affected and the surrounding family and has poor prognosis when onset is early. Among adolescents, early onset of depression predicts severe and persistent psychopathology in adult life and potential gains from preventing depressive disorders are considerable. This thesis investigated several aspects regarding the dissemination ...

We performed randomized, controlled experimental studies in an intact rat model and in isolated rat cardiomyocytes with the following aims: Paper I: To investigate the effects of epinephrine during hypothermia and after rewarming and determine hypothermia-induced effects on in vivo and in vitro cardiac β-receptor sensitivity. Paper II: To describe hemodynamic responses to the phosphodiesterase ...

The onset of experiencing symptoms of mental distress, such as depression and anxiety, is most common during the adolescent years, and is concurrent with a measured decrease in physical activity levels. Research on the association between physical activity and mental distress among adolescents find contradictory results, and the field is in need of more longitudinal research with validated measurements. ...