Blar i forfatter Doktorgradsavhandlinger (Helsefak) "Dawadi, Rangita"
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Biochemical characterization of Matrix Metalloproteinase-9 Binding interactions with two small non-peptide inhibitors and the proteoglycan serglycin & Processing of serglycin
Dawadi, Rangita (Doctoral thesis; Doktorgradsavhandling, 2020-04-17)The present work has a focus on biochemical characterization of the human matrix metalloproteinase-9. First part of the investigation focuses on the enzymes ability to form a complex with the small proteoglycan serglycin. Here the focus was on which amino acids and regions in both proMMP-9 and serglycin are important for the complex formation. For that, recombinant full-length proMMP-9 and various ...