Blar i forfatter Artikler, rapporter og annet (UB) "Aaberge, Lars"

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    • Clinical and echocardiographic parameters predicting 1- and 2-year mortality after transcatheter aortic valve implantation 

      Kjønås, Didrik; Schirmer, Henrik; Aakhus, Svend; Eidet, Jo; Malm, Siri; Aaberge, Lars; Busund, Rolf; Røsner, Assami (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-06)
      <p><i>Background:</i> Transcatheter aortic valve implantation (TAVI) has become a standard treatment option for patients with symptomatic aortic stenosis. Elderly high-risk patients treated with TAVI have a high residual mortality due to preexisting comorbidities. Knowledge of factors predicting futility after TAVI is sparse and clinical tools to aid the preoperative evaluation are lacking. The aim ...

    • Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study 

      Solberg, Ole Geir; Stavem, Knut; Ragnarsson, Asgrimur; Beitnes, Jan Otto; Skårdal, Rita; Seljeflot, Ingebjørg; Ueland, Thor; Aukrust, Pål; Gullestad, Lars; Aaberge, Lars (Journal article; Tidsskriftartikkel, 2019-02-21)
      <i>Introduction</i> - Many women undergoing coronary angiography for chest pain have no or only minimal coronary artery disease (CAD). However, despite the lack of obstructive CAD, they still have an increased risk of major adverse cardiovascular events. Pleiotropic effects of statins may influence microvascular function, but if statins improve microvascular function in unselected chest pain ...

    • Microvascular function and inflammatory activation in Takotsubo cardiomyopathy 

      Solberg, Ole Geir; Aaberge, Lars; Bosse, Gerhard; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Stavem, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-03)
      Aims - The aim of this study was to determine microvascular function in the acute phase of Takotsubo syndrome (TTS) and to identify inflammatory mediators that could reflect TTS-induced pathology.<p> <p>Methods and results - The study included 20 females [median age 65 years; interquarile range (IQR) = 58–70 years] with TTS according to the Mayo diagnostic criteria. During heart catheterization, ...

    • Rosuvastatin alters the genetic composition of the human gut microbiome 

      Kummen, Martin; Solberg, Ole Geir; Larsen, Christopher Storm; Holm, Kristian; Ragnarsson, Asgrimur; Trøseid, Marius; Vestad, Beate; Skårdal, Rita; Yndestad, Arne; Ueland, Thor; Svardal, Asbjørn M.; Berge, Rolf Kristian; Seljeflot, Ingebjørg; Gullestad, Lars; Karlsen, Tom Hemming; Aaberge, Lars; Aukrust, Pål; Hov, Johannes Espolin Roksund (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-25)
      The gut microbiome contributes to the variation of blood lipid levels, and secondary bile acids are associated with the effect of statins. Yet, our knowledge of how statins, one of our most common drug groups, affect the human microbiome is scarce. We aimed to characterize the effect of rosuvastatin on gut microbiome composition and inferred genetic content in stool samples from a randomized controlled ...