Blar i forfatter Artikler, rapporter og annet (UB) "Andreassen, Ole Andreas"

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    • Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment 

      Reponen, Elina Johanna; Tesli, Martin Steen; Dieset, Ingrid; Steen, Nils Eiel; Vedal, Trude Seselie Jahr; Szabo, Attila; Werner, Maren Caroline Frogner; Lunding, Synve Hoffart; Johansen, Ingrid Torp; Rødevand, Linn; Andreassen, Ole Andreas; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-28)
      Background: Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) associated with elevated cardiovascular disease (CVD) risk, including obesity. Leptin and adiponectin are secreted by adipose tissue, with pro- and anti-inflammatory properties, respectively. The second generation antipsychotics (AP) olanzapine, clozapine, and quetiapine have been associated with high leptin ...

    • The Association Between Cardiorespiratory Fitness and Cognition Appears Neither Related to Current Physical Activity Nor Mediated by Brain-Derived Neurotrophic Factor in a Sample of Outpatients With Schizophrenia 

      Holmen, Tom Langerud; Egeland, Jens; Andersen, Eivind; Mordal, Jon; Andreassen, Ole Andreas; Ueland, Thor; Bigseth, Therese Torgersen; Bang-Kittilsen, Gry; Engh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-25)
      <i>Objective</i>: We investigated whether levels of current physical activity (PA) contribute to the established relationship between cardiorespiratory fitness (CRF) and cognition in schizophrenia and whether brain-derived neurotrophic factor (BDNF) or its precursor proBDNF mediates this relationship. <p> <p><i>Method</i>: Sixty-one outpatients with schizophrenia spectrum disorders participated. ...

    • Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders 

      Reponen, Elina Johanna; Dieset, Ingrid; Tesli, Martin Steen; Mørch, Ragni Helene; Aas, Monica; Vedal, Trude Seselie Jahr; Haug, Elisabeth; Drange, Ole Kristian; Steen, Nils Eiel; Hope, Sigrun; Szabo, Attila; Gohar, Sherif Mostafa Mohamed Ahmed; Wedervang-Resell, Kirsten; Djurovic, Srdjan; Melle, Ingrid; Aukrust, Pål; Andreassen, Ole Andreas; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-10)
      <p><i>Background:</i> Cardiovascular disease (CVD) is a major cause of premature death in patients with psychotic disorders, where dyslipidemia occurs frequently. In the pathogenesis of these serious mental disorders, a low-grade inflammation seems to be a possible contributor. Concurrently, systemic inflammation and its interplay with dyslipidemia is a central driver in the pathogenesis of CVD. We ...

    • Increased Interleukin 18 Activity in Adolescents With Early-Onset Psychosis Is Associated With Cortisol and Depressive Symptoms 

      Wedervang-Resell, Kirsten; Friis, Svein; Lonning, Vera Louise Hiorth; Smelror, Runar; Johannessen, Cecilie Haggag; Reponen, Elina Johanna; Lyngstad, Siv Hege; Lekva, Tove; Aukrust, Pål; Ueland, Thor; Andreassen, Ole Andreas; Agartz, Ingrid; Myhre, Anne Margrethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-14)
      <i>Objective</i> - Evidence indicates that the pathophysiology of adult psychosis involves immune dysregulation, but its associations with stress are often not considered. The inflammatory cytokine interleukin (IL)-18, which is elevated in adult schizophrenia, is suggested to be sensitive to stress. We compared the associations of IL-18 with cortisol and clinical variables in adolescents with ...

    • Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation 

      Mochol, Monika; Taubøll, Erik; Aukrust, Pål; Ueland, Thor; Andreassen, Ole Andreas; Svalheim, Sigrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-29)
      <i>Purpose</i> - Proinflammatory cytokines seems to play a role in epileptogenesis independent of the underlying cause. The purpose of this study was to assess if IL-18 and its binding protein IL-18BP are related to epilepsy and could act as a predictive biomarker for epileptogenesis.<p> <p><i>Methods</i> - In this cross-sectional study, circulating levels of IL-18 and IL-18BP were analysed in ...